ProQuest Subject Index - Biochemistry at UNIVERSITY OF WASHINGTON

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You are viewing titles for UNIVERSITY OF WASHINGTON in the Biochemistry available through the UMI Dissertations & Thesis Gradwoorks site

Brain CaV1 channel/AKAP15 signaling complexes and the role of the distal C-terminus in CaV1 channel regulation in vivo	Characterization of bacterial homing endonuclease I-Ssp6803I

Proteomic techniques for studying protein expression in single cells from CNS cultures	Characterization of folate cycle enzymes in Plasmodium falciparum: Ligand binding properties of dihydrofolate reductase, thymidylate synthase, and serine hydroxymethyltransferase

Determinants of specificity and function in casein kinase I epsilon	Biochemical analysis of the Mycobacterium tuberculosis thymidylate synthases, ThyA and ThyX

Structural characterization and protein interactions involving the C-terminal domains of the breast cancer susceptibility protein, BRCA1, and its constitutive partner, BARD1	Biochemical role of the cag3 locus in H. pylori type IV secretion

Modeling protein interactions with designed peptides	Structural, biophysical, and biochemical characterization of the GAF domains from phosphodiesterases 5 and 6

The use of tandem mass spectrometry for comprehensive structural characterization of relevant biomolecules	The use of 13C carbonyl labeled residues to develop and refine site-specific NMR secondary structure analysis techniques

Computational enzyme design	Loss of DNA polymerase proofreading leads to cancer and tumor acceleration in mice

Structure determination, thermodynamic characterization, and computational redesign of the rare-cutting restriction endonuclease NotI	Recognition of the RNA polymerase II CTD by transcription termination factors

Synthesis and reactivity of an expanded family of superoxide reductase (SOR) model complexes using N-heterocyclic, thiolate-containing ligands: Towards a better understanding of structural-functional relationships	A protein-surface study using solid state nuclear magnetic resonance

Understanding barriers to in vivo gene delivery and developing nonviral vectors for more efficient gene delivery	Structural studies of biological pores by electron microscopy

Feature detection using high-resolution mass spectrometry: Software and applications for shotgun proteomics	Engineering gene repair reagents from the I-AniI homing endonuclease

Computational physical modeling and design of protein-DNA interactions	Tryptophantastic: Short peptides with stable folds

Insight into the mechanism of superoxide reductase from kinetic studies of an FeN4S biomimetic model complex	A volumetric score function for computational protein structure modeling and protein structure validation

Urea and temperature dependence of the physical and spectroscopic properties of the NADH oxidase from Thermus thermophilus HB8	Biomarker discovery via matrix assisted laser desorption/ionization time-of-flight mass spectrometry: Tales of broccoli and breast cancer

The role of metabolites in mechanism-based inactivation of cytochrome P450 enzymes	Modeling molecular mechanisms of mammalian mineralization

Characterization of folding pathways within fold families	Interactions between cardiac myosin binding protein-C and actin contribute to the regulation of muscle contraction

Structural studies of RNA-editing proteins in Trypanosoma brucei	Computational methods for the analysis of molecular dynamics simulations

Mapping the molecular determinants of AP-3 mediated vesicle trafficking	Disrupting HIV replication with structure-based design of Tat inhibitors

Designed hairpin peptides: Protein folding models and inhibitors of amyloid fibril formation	Dissection of a novel G-protein coupled receptor signaling network

Kinetochore Transport and Spindle Assembly in Saccharomyces cerevisiae	Species Variation in the Prion Protein

Acetyl-p-aminophenol and Acetyl-m-aminophenol: Using Structure-Toxicity Relationships to Identify Biomarkers for Hepatocellular Injury	Toward reconstitution of chromosome segregation in vitro

Growing Pains of Bacteriophage Lambda: Examination of the Maturation of Procapsids into Capsids	Skeletal and cardiac muscle-specific gene regulation by transcriptional elements of muscle creatine kinase intron-1

DNA Dynamics in the HhaI Recognition Sequence	Soft and Reactive Landing Studies on Plasma Pre-treated Silver Oxide Surfaces

Structure Prediction with Experimental Constraints	Structural Study of a Ubc12-Cul3-Rbx1-Dcn1-Cand1 Complex: Insights into the Assembly, Regulation, and Dynamic Topology of Cullin-RING Ubiquitin Ligases

Structural and Functional Characterization of Bacterial Secretion Systems Using Mass Spectrometry	The role of glucose in photoreceptor survival

Why Make Fat?: The Impact of de novo Fatty Acid Synthesis on Fat Storage, Reproduction, and Longetivy in C. elegans	Sensitive Optical and Microfluidic Systems for Cellular Analyses

Computational enzyme design: Engineering a novel catalyst, protein therapeutic, and carbon fixation pathway	AKAP220 Organizes Cytoskeletal Effectors to Influence Cell Shape and Behavior

Engineering of a Small Molecule-Regulated Switch for Studying Signaling Enzymes	A Chemical Genetic Method for Studying the Location-Specific Function of Protein Kinases

Biochemical Characterization of CYP4V2 and its Role in the Retinal Disease, Bietti Crystalline Dystrophy	Development of General Probes that Recognize a Specific Inactive Kinase Conformation

Characterization of Familial Amyotrophic Lateral Sclerosis Associated Mutants of the Human CuZn Superoxide Dismutase Monomer by Molecular Dynamics Simulations	The Coupled Process and Its Applications in Cellular Molecular Biology

A Multi-technique Characterization of Adsorbed Protein Films: Orientation and Structure by ToF-SIMS, NEXAFS, SFG, and XPS	The Pleiotropic Functions of Siderocalins in Antibacterial Defense, Endogenous Iron Transport and Tumorigenesis

Improving the expression of secretory and membrane proteins in Escherichia coli through folding pathway engineering	The Diagnosis of Lysosomal Storage Disorders by Measuring Enzyme Activity Using Tandem Mass Spectrometry

A Framework for Scientific Discovery through Video Games	Ultrasensitive Analysis of Single Neurons Using Capillary Electrophoresis with Laser Induced Fluorescence

Tools and Analyses for Differential Label-Free Proteomics Using Mass Spectrometry	Selection, Design and Applications of Solid Binding Peptides for Controlled Biomineralization

Influence of Protein Environment on Tryptophan Fluorescence	Coarsening dynamics of domains in lipid membranes

Investigation of Surface Interactions between Cytochrome b5 and Major Cytochrome P450 Isoforms	Label Transfer Reagents for the Study of Protein Kinase Complexes

From transposon to transcription factor: Genome-wide functional studies of the conserved primate CSB-PGBD3 fusion protein	Chemical Proteomic Tools for Studying Protein Kinase Active Sites

Computational de-novo design of ester hydrolases	Thiolate containing N-heterocyclic amine based ligands; Investigations of intermediates in O-2 and O2 reactivity and application towards new ligand design for modelling the active site of Superoxide Reductase

The cyclic-di-GMP receptors of S. Typhimurium: Testing their signaling specificity through second messenger affinity and their use as biosensors