ProQuest Subject Index - Molecular biology at UNIVERSITY OF SOUTHERN CALIFORNIA

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You are viewing titles for UNIVERSITY OF SOUTHERN CALIFORNIA in the Molecular biology available through the UMI Dissertations & Thesis Gradwoorks site

Mechanism of multiple-RRM-containing proteins interacting with their RNA targets	Statistical inference for factors involved in origin selection and replication timing in baker's yeast

Candidate gene association analysis by principal components	Glioblastomal treatment with 2,5-dimethyl-celecoxib (DMC) in vitro: Effects of additional chemotherapeutic drugs and tumor microenvironment, and, Inconsistencies among commonly used in vitro cell growth and survival assays

A new method to access presence of SV40 in malignant mesothelioma	The possible aberrant function of MBNL1 with insulin receptor (IR-B) mRNA in myotonic dystrophy type I

Construction of plasmid for constitutive and induced expression of secreted alkaline phosphatase in mammalian ovarian carcinoma cells	Identification of strain-specific DNA fragments of Actinobacillus actinomycetemcomitans by representational difference analysis

Clinical significance of oxyhemoglobin dissociation curves on the interpretation of pulse oximetry in sickle cell disease	Low molecular weight protein tyrosine phosphatase and insulin signal transduction

Obtaining insights into biomolecular interactions through surface plasmon resonance	Study of genetic variation in Asian Indians: Applications to complex diseases and endogamic exogamy

Genetic interaction between androgen receptor and Lef1 in bone mass control	Biological fabrication: Gradients produce failure resistant dental structures

Enhanced Burkitt's lymphoma cell killing by the combination treatments of bortezomib with celecoxib and 2,5-dimethyl-celecoxib (DMC)	The differential effects of selective COX-2 inhibitors on cell proliferation and induced ER stress in glioblastoma and pancreatic carcinoma cell lines

Structural characterization of pseudorepeat shuffled alpha-synuclein	Evaluation of the recommendation of vimentin as an internal control for standardization of immunohistochemistry

Glycine to alanine mutations affect the structure and dynamics of micelle bound alpha-synuclein	Investigating the role of SASH1 gene located on chromosome 6 in ovarian cancer

The expression of human carboxylesterases in normal tissues and cancer cell-lines	Molecular mechanisms of chemoresistance in breast cancer

Regulation of matrix metalloproteinase-9 in cutaneous wound healing	A Western blot analysis and immunohistochemical study of 4-day old mice teeth over-expressing amelotin during amelogenesis

Shifting topology of stem cells and molecular expression during feather regenerative cycling	Nuclear respiratory factor-1 regulation by PTEN signaling

Immune signatures of murine solid tumor models	Molecular mechanisms underlying the effects of CB1 antagonism in canine model of obesity

Snake venom proteins identification by nano high performance liquid chromatography tandem mass spectrometry	Isolation of secondary metabolites from Aspergillus nidulans

Examining perillyl alcochol in glioblastoma treatment and relating its effect to endoplasmic reticulum stress response to further advance its usage in combination treatment with dimethyl-celecoxib	Calorie restriction reduces liver steatosis in liver specific Pten deleted mouse model

Genetic engineering of thermally sensitive elastin-like polypeptide and its expression in HEK 293 cells	Modulation of host antigen presentation by herpes simplex virus 1

Investigation of anti-cancer and anti-apoptotic effects of novel-small molecule compounds	The mechanism of recruitment of Tip60 to ER target genes

Investigating the roles of BMI-1 and IGF-1 in promoting ESFT survival	The effects of overexpression of mtA: A putative cell membrane protein in mycobacteria

Production and characterization of proinsulin-transferrin fusion protein	Evaluation of the role of the basic helix-loop-helix transcription factor twist-2 in lymphocyte development and activation

The effects of ascorbates on Cr(VI)-induced cytotoxicity in C3H 10T1/2 mouse cells	Studies on the expression and function of the human TMEM56 protein

Implications of constitutively active Bone Morphogenetic Protein (BMP) signaling in skin morphogenesis and skin postnatal homeostasis	Comparative biomolecular and therapeutic effectiveness of collaborative integrative intervention in morbidly obese individuals

UVRAG maintains genomic integrity	Identification and characterization of post-translational modifications on histones: An on-line top-down mass spectrometry workflow for analysis using ProSight PTM

Determination of the causal potential of histone modifications on transcription and chromatin structure	Mechanism of repression of RNA Polymerase III-dependent transcription under hypoxia

A Synthetic Lethal Screen for NF-kB-Dependent Plasma Cell Disorders	Asymmetric cell division during neurogenesis, and the mechanisms behind gabaergic cortical interneuron development and specification

Cell cycle dependent regulation of cytokine signaling	The role of transcriptional coactivator CoCoA in the Wnt/beta-catenin-signaling pathway: Molecular mechanism of the N-terminal activation domain of CoCoA

Searching for and beyond replication origins	RCAN1-1Long is overexpressed in Alzheimer disease

In vivo and in vitro analysis of the epigenetic and genetic alterations in the progression of human bladder cancer	Transcriptional regulation in osteoblasts

Pattern mining across massive biological networks for functional discovery	Finding nuclear localization signals: A quantitative analysis

Kinetic studies of the interaction between U1A protein and U1 hairpin II RNA	Modulation of C/EBPalpha in the regulation of mouse amelogenin transcription during tooth formation

Identification of candidate DNA methylation markers in diffuse large B cell lymphoma	Over-expression of EphB4 by cancer cells provides survival advantage by interrupting death receptor-mediated apoptotic pathways

The mechanism of damage-induced mutations in Escherichia coli	Systematic analysis of single nucleotide polymorphisms in the human steroid 5-alpha reductase type I gene

C-Jun N-terminal kinase (JNK) mediated inhibition of pyruvate dehydrogenase (PDH) activity and its effect on mitochondrial metabolism during brain aging	Natural variation in Arabidopsis thaliana

A regulatory transcription module of ZBRK1/KAP1 complex and its signaling network in regulating DNA damage-responsive genes expression	Detecting and understanding differentiation of microarray expression data

Signal transduction in skin appendage pattern formation	Functions of Msx2 and Msx1 during mouse skull and hair follicle development

Effects of age-related glial activation on neurite outgrowth	Functional analyses of androgen receptor structure pertaining to prostate cancer

Investigation of two distinct chromatin events: H3 tail-mediated factor recruitment and H2A.X exchange	Co-chaperone influence on androgen receptor signaling and identification of androgen receptor genes in prostate cancer

Investigation of the molecular mechanisms underlying polarized trafficking of the potassium channels Kv4.2 and Kv1.3 in neurons	Repression of RNA polymerase III-dependent transcription by the tumor suppressors p53 and PTEN

Mechanisms for regulating the expression of the TATA-binding protein	Searching for mitogenic factors from the epicardium: PDGFA, IGF2 and more

Molecular misreading in Drosophila melanogaster	Identification of the targets required for the anti-tumor effect of celecoxib and its non-COX-2 inhibitory derivative

Nutritional competence in Escherichia coli: The use of double-stranded DNA as a nutrient	Mechanisms of long-term survival in Escherichia coli

Vitronectin misfolding and aggregation: Implications for the pathophysiology of age-related diseases	New tools for whole-genome analysis of DNA replication timing and fork elongation in Saccharomyces cerevisiae

Gene therapy for the prevention and treatment of leukemia	Rationalized immunotherapy by immune signature characterization

Identification of novel androgen receptor target genes in prostate cancer	How phosphorylation affects the biochemical regulation and targeting of activation induced cytidine deaminase (AID)

Essential role of the carboxyl-terminus for proper rhodopsin trafficking and "enlightenment" to the pathway(s) causing retinal degeneration in a mouse model expressing a truncated rhodopsin mutant	Promoters and insulators: Creating a safer integrating vector

An orchestra of glutamate receptors and transporters in synaptic transmission, plasticity and excitotoxicity	The function of TGF-beta signaling in palatal and dental epithelium during embryogenesis

Computational and experimental approaches for the identification of genes and gene networks in the Drosophila sex-determination hierarchy	The crystal structure of APOBEC-2 and implications for APOBEC enzymes

Biochemistry and reconstitution of V(D)J recombination in a purified system	Transcriptional co-activation functions of Msx homeodomain proteins by activating Hsf proteins

TGFbeta superfamily signaling is essential for the heart development	The human Lon protease in mitochondrial stress protection and aging

Integrin expression and signaling during palatal fusion	Molecular mechanisms of recurrent chromosomal rearrangements in human leukemias and lymphomas

DNA methylation inhibitors and epigenetic regulation of microRNA expression	Role of GRP78 and its novel cytosolic isoform GRP78va in regulating the unfolded protein response in cancer

Mechanisms of human skin cell migration and wound healing	Molecular analysis of high mobility group a2 (HMGA2) oncogenic function

Regulation of bone formation in vitro and in vivo	Runx2 interactions with the osteoblast genome

Studies on the alteration of DNA methylation in cancer	Hypoxia-induced adaptive responses

Development of DNA methylation biomarkers as an early detection tool for human lung adenocarcinoma	Characterization of Drosophila longevity and fecundity regulating genes

The effect of microbial load and autophagy on Drosophila immunity and life span	Molecular and genomic studies of sex determination in Drosophila

Development of DNA methylation based biomarkers for the early detection of squamous cell lung cancer	The transcriptional regulation of the pro-survival protein Grp78 by activating transcription factors and chromatin-modifying enzymes: Its upregulation in response to HDAC-inhibitor treatment and the therapeutic consequences

Structural studies of the IAPP membrane-mediated aggregation pathway	Influence of hormone replacement therapy with maximal eccentric exercise on estrogen receptor coregulators and skeletal muscle damage in postmenopausal women

Modulation of Runx proteins by steroid hormone receptors	Non-canonical TGF-beta signaling pathway in craniofacial development.

Transgenic biomarkers of aging in Drosophila melanogaster	The mechanism of R-loop formation in mammalian immunoglobulin class switch recombination

Structural features and modifiers of islet amyloid polypeptide: Implications for type II diabetes mellitus	Over-expression of superoxide dismutase in Drosophila melanogaster

The role of microRNAs in cancer	Utilizing chemotherapies to alter the balance between life and death in the ER stress response of cancer

Mechanism of human nonhomologous DNA end joining	Dynamics of Escherichia coli propagation, biofilm formation, and evolution

Computational construction and analysis of DNA and RNA	The endocytosis of enamel matrix protein derivatives

Sex-specific effects of Drosophila p53 on adult life span	Microbial detection of material defects and weakness

Epigenetic mechanisms driving bladder cancer	Ethanol-HIF-1 alpha axis in inflammatory gene expression in liver cells

Mitotic regulation in ovarian epithelial tumors approaching in vitro crisis	A novel role for hypoxia-inducible factor-1alpha (HIF-1alpha) in the regulation of inflammatory chemokines and leukotriene expression in sickle cell disease

Tissue specific action of Msx genes in the regulation of skull vault development	The genetic axonal labeling of Trpm8 neurons

Regulation of axonal development by the cGMP signaling pathway	Structure and function of archaeal MCM helicase

Hutchinson Gilford Progeria Syndrome and the role of lamin A in the onset of the progeroid cellular phenotype	Differential role of two coactivators, CCAR1 and CARM1, for dysregulated beta-catenin activity in colorectal cancer cell growth and gene expression

Structure and regulation of lymphoid tyrosine phosphatase (LYP) in autoimmune response	Study of dendritic cell-specific lentivector vaccine system

The study of the role of bone morphogenetic proteins in prostate cancer progression	Chorion gene amplification in Drosophila melanogaster

Mechanistic studies of the disintegrin contortrostatin and characterization of the recombinant protein vicrostatin	Harnessing the power of stem cell self-renewal pathways in cancer: Dissecting the role of BMI-1 in Ewing's sarcoma initiation and maintenance

Exploring alternative roles of visual arrestin 1 in photoreceptor synaptic regulation and deciphering the molecular pathway of retinal degeneration using mouse knockout technology	The S. pombe Mst1 histone acetyltransferase is required for genome stability

Investigating the role of STAT3 in mouse and rat embryonic stem cell self-renewal and differentiation	Structure-function studies on the mammalian intestinal dipeptide transporter hPEPT1

Elements of photoreceptor homeostasis: Investigating phenotypic manifestations and susceptibility to photoreceptor degeneration in genetic knockout models for retinal disease	Identification of novel protein-protein interactions and functional analysis in the mouse photoreceptor of the hypothetical protein FLJ33282-Als2cr4 and the small Rho GTPase, Rnd2

Pre-transplant conditioning and the role of the microenvironment during hematopoietic reconstitution	Anti-Hu immuno-responsiveness in small-cell lung cancer

Role of DNA methyltransferases 3A and 3B in inheritance of DNA methylation patterns	Role of endoplasmic reticulum chaperones GRP78 and GRP94 in regulating unfolded protein response and cell survival

Characterization and functional study of a novel human protein SFMBT, and PR-Set7 histone methyltransferase	Pten deletion induced tumor initiating cells: Strategies to accelerate the disease progression of liver cancer

Molecular and computational analysis of spin-labeled nucleic acids and proteins	A structure based study of the HIV restriction factor APOBEC3G

Targeting chromatin modification in human cancer: SMYD3 mediated ERalpha Transcription regulation. Cooperative role between H3.3 and HP1gamma	Measuring, Modeling and Identifying Factors That Influence Eukaryotic DNA Replication

Bimodal effects of bone morphogenetic proteins in prostate cancer	Bidirectional plasticity supports learning and post-ischemic functional recovery in the rat striatum

Investigation of epigenetics in cell populations using three-dimensional quantitative DNA methylation imaging	The study of the aspergillus nidulans metabolome in the post-genomic era

The role of pknG in mycobacterial physiology, including M. tuberculosis	Endothelial neuropilin disruption in mice causes DiGeorge syndrome-like malformations independent of Tbx1

The diverse roles of Smads in dorsal spinal cord development	The importance of Dfp1 in alkylation damage response and meiosis

Two faced coregulator: Coactivation and corepression of transcription by histone methyltransferase G9a	The centromere: Replication, recombination, reassembly

Comparison of cationic and amphipathic cell penetrating peptides in the internalization and intracellular localization of cytochrome c conjugates	Cell penetrating peptide-based polyplexes for siRNA delivery

The peptide angiotensin-(1-7) as a novel treatment for complications induced by type 2 diabetes mellitus	DNA deamination and binding properties of wild type and HIGM2 mutants of activation induced cytidine deaminase

The role of the proteasome & its regulators in adaptation to oxidative stress	Design and discovery of small molecules inhibiting the interaction of cellular LEDGF/p75 and HIV-1 integrase

DNA methylation changes in the development of lung adenocarcinoma	The role of Cdc7 in replication fork progression in response to DNA damage

Targeting Bcl-2 family proteins and plasminogen activator inhibitor-1 in tumor cell apoptosis	Survival and evolution of Shewanella oneidensis MR-1: Applications for microbial fuel cells

Progesterone receptors in the rat brain and their role in steroidal regulation of neurite outgrowth	Exploring three-dimensional organization of the genome by mapping chromatin contacts and population modeling

Maf1 is a novel target of the tumor suppressor PTEN and a negative regulator of lipid metabolism	Physiological roles and evolutionary implications of alternative DNA polymerases in Escherichia coli

Mechanism study of SV40 large tumor antigen ATPase and helicase functions in viral DNA replication	Multiple functions of the PR-Set7 histone methyltransferase: From transcription to the cell cycle

Identifying allele-specific DNA methylation in mammalian genomes	Epigenetic plasticity of cultured female human embryonic stem cells and regulation of gene expression and chromatin by PR-SET7 mediated H4K20me1

Biochemical characterization and structural analysis of two hexameric helicases for eukaryotic DNA replication