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You are viewing titles for UNIVERSITY OF PENNSYLVANIA in the Pharmacology available through the UMI Dissertations & Thesis Gradwoorks site
 
Investigating the mechanisms underlying cognitive impairments and seizure susceptibility following traumatic brain injury
 Cardiovascular rhythms and the molecular clock
 
Effects of atomoxetine on nicotine abstinence symptoms
 Effects of structure on post-transcriptional gene silencing
 
15-lipoxygenase-1 mediated formation of endogenous GSH- and RNA-adducts and its impact on GSH/GSSG homeostasis in monocytes/macrophages
 Alterations in gene expression at key points in the addiction cycle
 
Protease inhibitor development and substrate specificity profiling
 Role of aldo-keto reductase enzymes in polycyclic aromatic hydrocarbon trans-dihydrodiol activation in human lung cells
 
Enhanced sensitivity of the MRL/MPJ mouse to the neuroplastic and behavioral effects of acute and chronic antidepressant treatments
 The molecular imaging of herpes simplex virus type-1 thymidine kinase reporter gene expression: Novel [18F] labeled reporter probes
 
The role of complement regulatory proteins in prevention of cell injury
 The mechanistic and therapeutic implications of tumor hypoxia in the TRAIL signaling pathway
 
Small molecule inhibitors of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism
Novel roles for Pdx1 in the endocrine pancreas
 
Intra- and inter-molecular interactions regulate the activity of the Rac-GAPs alpha2- and beta2-chimaerins
 Role of claudin-5 and hemodynamics in endothelial permeability and susceptibility to atherosclerosis
 
Near-infrared enzyme-activated fluorescent phospholipids for molecular imaging
 The role of retained intron sequences in neuronal dendritic mRNA
 
Antidepressant and anxiolytic-like effects of kappa-opioid receptor antagonists in Wistar Kyoto rats
 Development of serotonin transporter brain imaging agents for use in positron emission tomography and single photon emission computed tomography
 
Developing novel platelet-based targeting strategies for thrombolytics
Understanding and improving platelet-delivered Factor (F) VIII hemostatic efficacy in hemophilia A mice
 
Adolescent development determines the effects of agonistic social stress on rat behavior and locus coeruleus physiology
 The role of 15-lipoxygenase-1- and cyclooxygenase-2-derived lipid mediators in endothelial cell proliferation
 
Role of Rap signaling in the regulation of ERK activation and cell-cell adhesion
 Liquid chromatography -- mass spectrometry for protein biomarker discovery in pancreatic adenocarcinoma
 
Genetic Polymorphisms and Antifolate Drug Treatment Can Alter Folate/Homocysteine Metabolism and Inflammatory Protein Profile
 Cellular characterization of the receptors for the C5a anaphylatoxin and their contributions to the innate and adaptive immune responses
 
NMDA receptor dysfunction and development of translational biomarkers for autism and schizophrenia
 Measuring biomarkers of Friedreich ataxia: Implications for clinical research