ProQuest Subject Index - Molecular biology at UNIVERSITY OF PENNSYLVANIA

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You are viewing titles for UNIVERSITY OF PENNSYLVANIA in the Molecular biology available through the UMI Dissertations & Thesis Gradwoorks site

Role of LINE-1 retrotransposon in genome evolution: Mechanisms of L1 integration and L1-mediated creation of new genes	Molecular and physiologic significance of the nuclear receptor corepressor-HDAC3 complex

Molecular and cellular mechanisms of axon guidance during visual system development in zebrafish	Roles of BMP signaling in spatiotemporal coordination of embryonic axial patterning

Histone H2B deubiquitylation and transcriptional control in the yeast Saccharomyces cerevisiae	Regulation of immunoreceptor and integrin signaling by the adapter protein SLP-76

The role of protein phosphatase 1 in the Drosophila circadian clock	Histone modifications and histone modifying enzymes in the budding yeast Saccharomyces cerevisiae

The role of T-bet and eomesodermin in effector and memory CD8+ T cell differentiation	Non-clathrin endocytosis: Mechanisms of regulating Arf6 and its endocytic pathway

Theory of optical nanoantennas and arrays based on surface plasmon resonance of plasmonic nanoparticles	Interplay between SCF and CDK complexes in the control of cellular proliferation

Structural and functional studies on the retinoblastoma and p300/CBP tumor suppressor proteins and their regulation by viral oncoproteins	Regulation of circadian rhythms and adipogenesis by the nuclear receptor Rev-erbalpha

Mechanism of recruitment of p53-binding protein 1 (53BP1) to DNA double-strand breaks	Human blood coagulation on matrix protein microarrays under venous and arterial flow

Allocating energy utilization for growth and metabolism: The interplay between insulin and inflammatory signaling in Drosophila melanogaster	Integration of growth factor and nutrient signaling in the regulation of cellular and organismal growth

The role of von Hippel-Lindau mutation in polycythemia and pulmonary hypertension	Prime-boost vaccine strategies using adenovirus and adeno-associated virus vectors to induce CD8+ T cell responses against human immunodeficiency virus type I

The winged helix transcription factor Foxl1 in proliferation and homeostasis of the gastrointestinal tract and liver	Interaction of gp340 with HIV and its contribution to heterosexual transmission in females

Influence of Tie2 on tumor vascular signaling, integrity, and response to therapy	PERK-regulated protein translation mediates cell cycle arrest and survival during the Unfolded Protein Response

Characterizing the role of the exocyst component Exo70 in exocytosis and actin dynamics in budding yeast Saccharomyces cerevisiae	The emergence of embryonic dorsal-ventral pattern through the interactions of BMP ligands with their receptors and modulators

Signaling pathways regulating amyloid precursor protein and Abeta generation: Roles for isoprostane-induced thromboxane receptor signaling and chronic Akt activation in Alzheimer's disease	Structural and biochemical studies of site-specific recombinases

Molecular recognition and catalysis in sortase A from Staphylococcus aureus	Myostatin regulation and function in the heart

Insulin regulates adipocyte lipolysis via a compartmentalized Akt-independent signaling pathway	Proteolytic processing of the guidance receptor Roundabout regulates its activity

DNA damage response pathways in cancer chemotherapy: Investigating roles of PARP and PP2A	Jagged1 in pancreatic endocrine and duct development

Ars2 links the nuclear cap binding complex to RNA processing and cell proliferation	Genome-wide orchestration of adipocyte biology by PPARgamma and C/EBP

The mechanistic and therapeutic implications of tumor hypoxia in the TRAIL signaling pathway	Novel contributions of Pdx-1 to pancreatic beta-cell adaptation to insulin resistance

Ezrin and moesin are required for T cell function	Tonic B cell antigen receptor signals supply an NF-kappa substrate, p100, for prosurvival BLyS signaling

Spatial regulation of Cdc42 by its GTPase-activating proteins Rga1 and Bem2 in budding yeast Saccharomyces cerevisiae	Investigation of the mechanisms by which histone acetylation and sleep deprivation modulate hippocampal function

Maternal depletion of CTCF reveals multiple functions in transcription and development	Functional characterization of Alpha Hemoglobin Stabilizing Protein in hemoglobin synthesis

ATR and H2AX cooperate in maintaining genome stability under replication stress	Intra- and inter-molecular interactions regulate the activity of the Rac-GAPs alpha2- and beta2-chimaerins

Rational design of novel transcriptional regulators	Defining the mechanism by which glycoprotein D triggers HSV fusion and entry

Membrane protein sorting and trafficking in budding yeast Saccharomyces cerevisiae endocytic system	Regulation of H2AX phosphorylation density around a defined double stranded DNA break in chromatin

Role of resistin in the central nervous system regulation of glucose and energy homeostasis	Cooperative relationships between Brca2, timeless, and other genome maintenance regulators for ensuring genomic integrity during DNA replication

Role of the forkhead transcription factor, fktf-1, in the development of Strongyloides stercoralis	Host cell factors involved in Ebola virus entry and spread

Olfactory marker protein is critical for functional maturation of olfactory sensory neurons in mice	RNA-dependent recruitment of ORC to the Epstein-Barr virus origin of replication

Constitutive non-canonical NF-kappaB signaling in pancreatic cancer	Role of amyloid precursor protein and amyloid-beta in Alzheimer's disease: Modulation of APP processing detection of Abeta oligomers, and their role in the pathogenesis and treatment of AD

Modulation of the immune response at systemic and mucosal sites by DNA vaccine adjuvants in HIV and influenza models	The role of retained intron sequences in neuronal dendritic mRNA

Gaining CXCR4 utilization for HIV and SIV: Mechanisms and consequences	Unique transcriptional and chromatin profiles of memory CD8+ T cells

Investigation of the mechanisms involved in radiosensitization of squamous carcinoma cells by the chemopreventive agent curcurmin	The circadian clock as a sensor of cell metabolic state: Interactions between nutrients, growth factors, and the mammalian clock machinery

K-Ras oncogene-induced ROS detoxification promotes tumorigenesis	Platelets mediate separation of blood and lymphatic vessels

Novel roles for the SMC5/6 complex and DNA helicase MPH1 in template switch recombination	Molecular mechanisms of the Birt-Hogg-Dube tumor suppressor

The role of Akt2 in hepatic lipid metabolism	Functions of DNA damage response factors in lymphocyte development and transformation

Protein Partners and Post-translational Modifications: Towards Understanding the Regulation of Argonaute Proteins	The impact of capsid structure on the immune response to adeno-associated viral vectors

Nucleoside modifications suppress RNA activation of cytoplasmic RNA sensors	Rac1-mediated actin cytoskeleton remodeling and monolayer barrier properties of stretched alveolar epithelial cells

Characterization of thap10 and thap11 as transcriptional repressors in DNA damage and colon cancer progression	Understanding and improving platelet-delivered Factor (F) VIII hemostatic efficacy in hemophilia A mice

The basis of VCP-mediated degeneration: Insights from a Drosophila model of disease	The role of preMBT transcription in Xenopus development

Genomic methods for studying the post-translational regulation of transcription factors	Regulation of CCR5 use on primary CD4+ lymphocytes by R5X4 HIV-1

Fatty Acid Metabolism Mediated by 12/15-Lipoxygenase is a Novel Regulator of Hematopoietic Stem Cell Function and Myelopoiesis	The role of GATA1 acetylation during erythroid development

Adeno associated virus vectors in gene therapy for hemophilia B: Random versus targeted genomic integration	Characterization of bacterial factors that promote resistance to complement-mediated opsonophagocytic killing and lysis

Roles of Protein Factors in Regulation of Imprinted Gene Expression	The fibronectin EIIIA splice variant promotes hepatic stellate cell motility and liver fibrosis via alpha9beta1 integrin

Functional analysis of the Cdk7/cyclin H/Mat1 complex in mouse embryonic stem cells and embryos	Ubiquitination and Deubiquitination in Cellular Responses

Transcriptional Integration of Wnt and Nodal Signals in the Establishment of the Spemann Organizer	MgrB and periplasmic redox balance contribute to negative feedback in the PhoQ/PhoP two-component system of Escherichia coli

Tumorigenic adenovirus 12 cells evade NK lysis by reducing the expression of NKG2D ligands	Structural and biochemical studies of the SMN oligomerization domain: A novel glycine zipper

The molecular mechanism for vegetative phase change: Regulation of miR156 expression and action	Sporadic clear cell renal cell cancer and the HIFs

Multiscale modeling of the ErbB receptor tyrosine kinase signaling network through theory and experiment	Structural, biochemical, and cell biological characterization of RAB7 mutants that cause peripheral neuropathy

Viral diversity by deep sequencing: Approaches to analyzing effects of anti-HIV treatments	Relationships between decorin and biglycan, structure and tendon mechanics using mutant mouse models

Decoding cytochrome c oxidase biogenesis: New insights into copper trafficking	A notch above bowl: Specification of niche cells in the Drosophila testis

HIV Transmission, Entry, and Gene Therapy	Molecular insight into mechanisms of CAG-repeat RNA toxicity in polyglutamine disease from Drosophila

Lysine post-translational modifications of Saccharomyces cerevisiae chromatin proteins	The role of the pituitary-specific element DNAse I hypersensitive site II in the human growth hormone locus control region

Inducible deletion of Dicer or Drosha reveals multiple functions for miRNAs in postnatal epidermis and hair follicles	Design and application of photoactivatable oligonucleotides

PHoQ: Structural and mechanistic investigations into an important bacterial sensor kinase	HIV Gag expression during latent infection: Is the reservoir really invisible?

Periostin and its role in promoting invasion in the tumor microenvironment of esophageal cancer