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You are viewing titles for UNIVERSITY OF PENNSYLVANIA in the Biophysics available through the UMI Dissertations & Thesis Gradwoorks site
 
Biological molecules as protectors against cellular damage caused by environmental extremes: The role of protectant-water interactions
Measuring, modelling, and dissecting the cellular mechanical response
 
Polymersome and worm-like micelle formulations for targetable drug and oligonucleotide delivery
Single molecule study on lipid vesicles and proteins by confocal microscopy
 
Soft matter systems simulated by molecular methods
The effects of disruption of cytoskeleton polymers on the rheological properties of cultured mammalian cells in the cortical and perinuclear regions
 
Studies of intermolecular and intramolecular coupling using dual frequency 2D IR photon echo spectroscopy
Interfacial characteristics of a gas bubble immersed in a surfactant and protein laden fluid: Experimentation and modeling
 
Structural and functional studies on the retinoblastoma and p300/CBP tumor suppressor proteins and their regulation by viral oncoproteins
Sketching nature's energy function: Designing helices that target transmembrane proteins and creating software for further design
 
Nanoscale particle binding in silico: HIV docking and multivalent recruitment under flow
De novo design and characterization of a family of metalloporphyrin proteins: The porphyrin assemblers
 
Diversity in molecular recognition of phospholipids by PH domains: An examination of three unusual PH domain-phospholipid interactions
Understanding the folding mechanisms of small model proteins
 
Controlling the morphology of F-actin cytoskeleton: A simulation study
Lipid organization in biomimetic model systems - oligomerization, domain formation, and diffusivity
 
Spectroscopic studies of the early events in membrane-mediated and cofactor-induced protein folding kinetics
Structural and biochemical studies of site-specific recombinases
 
Studies of synthetic protein models designed for biomolecular materials applications and model ion channels via molecular dynamics simulations
Molecular recognition and catalysis in sortase A from Staphylococcus aureus
 
Pellino proteins contain a non-canonical FHA domain that mediates the interaction with IRAK1
The regional cerebral metabolic rate of oxygen consumption with proton detected 17O MRI during precision 17O2 inhalation
 
Cross-talk between bacterial two-component circuits
Rational design and characterization of beta-peptides, a non-natural peptidomimetic scaffold
 
Rotating frame magnetic resonance imaging techniques
Modeling the bioenergetics of protein-mediated membrane deformation
 
Probabilistic computational protein design: Advances in methodology and the incorporation of non-biological molecular components
Single-molecule biophysical assays with electrokinetics
 
Structure and mechanics of proteins from single molecules to cells
Optimization of multidimensional nuclear magnetic resonance spectroscopy, for resolution and sensitivity, through application of radial sampling
 
Shortest geometric paths analysis in structural biology
Structural studies of large integral membrane proteins in reverse micelles by solution nuclear magnetic resonance
 
Spectroscopic and x-ray scattering studies of the interaction of a volatile general anesthetic with ion channel proteins
A new approach to understanding biological control of quinone electrochemistry
 
New fluorescence methods for protein folding and conformational studies
Deconvoluting the engineering and assembly instructions for Complex III activity
 
A new approach to understanding biological control of quinone electrochemistry
Interplay of extrinsic and intrinsic cues in cell-fate decisions
 
Single Molecule Studies of Myosin-Ib
Structure-based mechanism of proton transport through the influenza A M2 protein
 
Structure-based design of inhibitors targeting influenza A virus M2 proton channel (A/M2)
A study of molecular adsorption and transport at cell membrane and biologically relevant surfaces by Second Harmonic Generation
 
Single molecule investigations of DNA looping using the tethered particle method and translocation by acto-myosin using polarized total internal reflection fluorescence microscopy
Using structural bioinformatics to model and design membrane proteins
 
On the nature of the hydrogen bond and biomolecular solvation
Identification of cell migratory cues by control of microenvironmental adhesion
 
Folding and Assembly of Cytoskeletal Proteins Under Force - From Single Molecule Studies of Dystrophin to Studies of Intact Cells
Examining the coupling of the mechanical and chemical functions of myosin family members using single molecule and bulk solution techniques
 
Indirect detection of axonal architecture with Q-space imaging
Unveiling the Molecular Mechanisms Regulating the Activation of the ErbB Family Receptors at Atomic Resolution through Molecular Modeling and Simulations
 
Diffusionless transformations in DNA-mediated alloys of nano-colloids
Structural and biochemical studies of the SMN oligomerization domain: A novel glycine zipper
 
Protein design and material design at the nano-bio interface
Structural studies of acetylpolyamine amidohydrolase
 
Entropic elasticity of polymers and their networks
On the folding and conformation of peptides and the development of novel methods for their study
 
Interplay of ethanol and cholesterol in the neutrophil membrane: Effects on membrane and cell mechanics and neutrophil adhesion
The structural proteomics of S-nitrosylation: From global identification to elucidating protein function through structural bioinformatics
 
Single-molecule diffusion as a probe of the structure and function of biological systems
Inhaled Oxygen as a Quantitative Intravascular MRI Contrast Agent
 
Engineering an artificial, multifunctional oxidoreductase protein maquette
The integrin equilibrium: Balancing protein-protein and protein-lipid interactions
 
Probing DNA-induced colloidal interactions and dynamics with scanning-line optical tweezers
Protein hydrogen exchange, dynamics, and function
 
Efficient neural population codes
Using structural bioinformatics to understand and design protein structures and interactions
 
The induction, decay and diffusion of a bacterial tetracycline efflux pump
PHoQ: Structural and mechanistic investigations into an important bacterial sensor kinase
 
Matrix elasticity drives cytoskeletal polarization and guides stem cell migration
Endothelial cell assembly, migration, and force generation in engineered microenvironments