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You are viewing titles for UNIVERSITY OF PENNSYLVANIA in the Biomedical engineering available through the UMI Dissertations & Thesis Gradwoorks site
Dexamethasone-spermine as a local drug and gene delivery vehicle for improved pulmonary gene therapy
Mechanics of head impact in infants
Polymersome and worm-like micelle formulations for targetable drug and oligonucleotide delivery
Biophysical mechanisms for precise temporal signaling in the auditory system
Identifying transcriptional regulatory modules and networks by integrative approaches
Simulated and experimental coagulation of human blood
Quantification of neutrophil spreading and migration and the development of a novel model for neutrophil motility
In-vivo optical imaging and spectroscopy of cerebral hemodynamics
Photolabile polyethylenimines for light-activated nucleic acid delivery
Fluorescence spectroscopy and imaging of myocardial infarction
Magnetic resonance studies of architecture and composition of bone
The interplay of cell tension, elasticity, and adhesion: From the simple red cell membrane to differentiation and signaling muscle cells
Nanoscale particle binding in silico: HIV docking and multivalent recruitment under flow
Human blood coagulation on matrix protein microarrays under venous and arterial flow
Simulations of neutrophil rolling dynamics and the transition to firm adhesion
Development and application of Tat-near-infrared-emissive polymersomes for in vivo optical imaging of dendritic cells
Dentate gyrus control of perforant path throughput to CA3 in a computational model
Engineering nanoparticle adhesive properties for selective targeting of cardiovascular disease
An in vivo model of transient cervical nerve root compression: Thresholds for mechanical allodynia and neuronal responses
Tendon mechanical properties and measures of shoulder function are altered after multiple tendon detachment in a rat rotator cuff model
Interaction of excitatory and inhibitory synaptic inputs in neurons of the thalamocortical network during normal and pathological brain activity: Computational modeling and dynamic clamp in vitro
Measurement of pulmonary structure and function parameters with hyperpolarized 3He magnetic resonance imaging
Osteogenic differentiation of human dermal fibroblasts
Non-invasive imaging of breast cancer with diffusing near-infrared light
Lipid organization in biomimetic model systems - oligomerization, domain formation, and diffusivity
Extracellular matrix stiffness augments integrin and growth factor receptor signaling to drive malignant transformation
Mechanical interactions between the supraspinatus and infraspinatus tendons: Effect of supraspinatus tendon tear, load, repair technique and joint position on strain in the infraspinatus and supraspinatus tendons
Quantitative imaging and high-throughput analysis of RNA in living cells using molecular-beacon conjugates
Multi-site analyses of endothelial phenotypes at locations of varying susceptibilities to atherogenesis in normal and hypercholesterolemic swine
Endothelial phenotypes in a hypercholesterolemic swine model of early aortic valve sclerosis
An engineering approach to understanding painful facet-mediated injury: Insights on biomechanics and neuropeptide responses in a rat model
Differential behavior of fetal and adult fibroblasts: Implications for regenerative tissue healing
The regional cerebral metabolic rate of oxygen consumption with proton detected 17O MRI during precision 17O2 inhalation
Filamentous and spherical polymer nanocarriers for enzyme therapeutics
Statistical tissue segmentation of neonatal brain MR images
Cell-based and biomaterial approaches to connective tissue repair
Altered and restored function after reduced nucleus pulposus glycosaminoglycan content in the rat lumbar intervertebral disc
The functional roles of dopaminergic modulation and local inhibition in the striatum
Cell-specific inflammatory spinal responses in cervical nerve root compression: Cellular reactivity and cytokines in pain
Carbon-based nanoprobes for cell nanosurgery & biological applications
Spatio-temporal deformation analysis of cardiac MR images
Functional characterization of the self signal CD47: From macrophage clearance mechanisms to therapeutic development
Near-infrared enzyme-activated fluorescent phospholipids for molecular imaging
Quantitative analysis of immune cell motility and mechanics on hydrogel substrates
Anisotropic, inhomogeneous and nonlinear structure-function of human supraspinatus tendon
Sepsis and stretch increase alveolar epithelial permeability
Effect of head rotation direction on closed head injury in neonatal piglets
Head injury biomechanics in toddlers: Integrated clinical, anthropomorphic dummy, animal and finite element model studies - implications for age-dependence
Structure and mechanics of proteins from single molecules to cells
Development and characterization of photocrosslinkable hyaluronic acid hydrogels for cartilage regeneration
A systems approach to cellular signal transduction
Mechanical and chemical effects in adhesion of thin shell structures
Degeneration affects the structural and tissue mechanics of the intervertebral disc
Biochemical and biomechanical modulation of nucleus pulposus cells encapsulated in novel cellulose-based hydrogels
Unsupervised classification of high-frequency oscillations in neocortical epilepsy and control patients
Microfluidic focal injury models of thrombosis and hemostasis
Mechanisms of astrocytic calcium wave propagation and in vitro hippocampal cell death are determined by the magnitude of mechanical injury
Shape representation in primate visual area 4 and inferotemporal cortex
Interplay of extrinsic and intrinsic cues in cell-fate decisions
Statistical medial model for cardiac segmentation and morphometry
Quantitative cardiac imaging to evaluate stem cell therapy of myocardial infarction
Evaluation of quantitative MR imaging biomarkers for assessment of breast cancer risk
Development as a new paradigm for improved tendon healing: A characterization of neonatal tendon development, healing during development and an investigation into differential parameters during accelerated healing
Rac1-mediated actin cytoskeleton remodeling and monolayer barrier properties of stretched alveolar epithelial cells
Computational modeling of protein kinases: Molecular basis for inhibition and catalysis
Integrating electrophysiological, mechanical, and optical methods to define the mechanisms of painful facet joint injury
Dendritic cell migration and traction force generation in engineered microenvironments
MicroBioRobots for single cell manipulation
Calpain mediated proteolysis of voltage gated sodium channels and its role in pathological development after traumatic brain injury
Mapping trabecular bone fabric tensor by in vivo magnetic resonance imaging
Meniscus tissue engineering with nanofibrous scaffolds
Combinatorial polymer synthesis and high-throughput screening technology to identify optimal approaches for mineralized tissue engineering
Characterizing connectivity in brain networks using magnetic resonance imaging
Enhancing mesenchymal stem cell chondrogenesis for cartilage tissue engineering
Acellular and radically polymerized biodegradable materials to control tissue interactions after myocardial infarction
Integrating theoretical and experimental methods for multi-scale tissue engineering of the annulus fibrosus of the intervertebral disc
Quantitative molecular MRI of intervertebral disc degeneration
Identification of cell migratory cues by control of microenvironmental adhesion
Quantitative mapping of lung ventilation using hyperpolarized gas magnetic resonance imaging
Regulation of TGF-B1-induced apoptosis and epithelial-mesenchymal transition by matrix rigidity
Indirect detection of axonal architecture with Q-space imaging
Unveiling the Molecular Mechanisms Regulating the Activation of the ErbB Family Receptors at Atomic Resolution through Molecular Modeling and Simulations
Regulation of contractility in mammalian cells by soluble, adhesive and mechanical cues of the microenvironment
Chemical and biological strategies for improving the sensitivity of SPIO-enhanced MR imaging
An in vitro and in silico investigation of the role of NMDA receptor subtypes following mechanical injury
Multiscale modeling of the ErbB receptor tyrosine kinase signaling network through theory and experiment
High throughput screening for the enhancement of adeno-associated virus type 2 transduction
Lattice kinetic Monte Carlo simulations of platelet aggregation and deposition
Interplay of ethanol and cholesterol in the neutrophil membrane: Effects on membrane and cell mechanics and neutrophil adhesion
Optimization and translation of MSC-based hyaluronic acid hydrogels for cartilage repair
Inhaled Oxygen as a Quantitative Intravascular MRI Contrast Agent
Enhancing meniscus repair through biomaterial design
Generative-discriminative low rank decomposition for medical imaging applications
ICP-MS analysis of lanthanide-doped nanoparticles: A quantitative and multiplexing approach to investigate biodistribution, blood clearance, and targeting
NMDA receptor dysfunction and development of translational biomarkers for autism and schizophrenia
Collagen fiber re-alignment and uncrimping in response to loading: Determining structure-function relationships using a developmental tendon mouse model
Combined fluorescence imaging of hippocampal dentate gyrus neural activity
Induction of cellular senescence as a novel therapeutic strategy for melanoma treatment
Engineering hyaluronic acid hydrogel degradation to control cellular interactions and adult stem cell fate in 3D
Development and validations of a deformable registration algorithm for medical images: Applications to brain, breast and prostate studies
Dynamics of endogenous cardiac repair and methods for enhanced post-injury cell therapy
Spatially and temporally controlled mechanical signals to direct human mesenchymal stem cell behavior
Tunable acellular hyaluronic acid hydrogel systems to attenuate left ventricular remodeling
Endothelial cell assembly, migration, and force generation in engineered microenvironments