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UNIVERSITY OF MICHIGAN
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You are viewing titles for UNIVERSITY OF MICHIGAN in the Molecular biology available through the UMI Dissertations & Thesis Gradwoorks site
The role of Polycomb group protein EZH2 in cancer progression
Molecular determinants of ATP binding to P2X2 ion channels
The role of negatively charged amino acids in channel function, pH potentiation, and zinc modulation of the ATP-gated rat P2X2 receptor
Collective dynamics of kinesin-1
tRNA genes affect multiple aspects of local chromosome behavior
Biochemical analysis of the regulation of vesicle fusion, peroxisomal protein import and proteolytic processing in eukaryotes
Mutations in PI(3,5)P2 signaling and neurodegeneration in mouse and human
Cellular roles of the inhibitor of apoptosis protein c-IAP1
Metabolic cues and regulatory proteins that govern Legionella pneumophila differentiation and virulence
Assembly, spatial distribution, and secretion activity of the curlin secretion lipoprotein, CsgG
Applications of functional genomics in studies of yeast signaling networks and genome structure
Central inhibitory effects of glucocorticoids on reproductive function: Permissive role of estradiol
Tissue specific deletion of ZBP-89 in the mouse intestine results in expansion of goblet and Paneth cell lineages
Target gene selection in the wingless signaling pathway
Insulin-like growth factor signaling during myogenesis
The role of the TSC-mTOR pathway on the regulation of the hematopoietic stem cells
Plant stress responses: Autophagy and senescence
Molecular epidemiology, racial/ethnic differences and chemoprevention of breast cancer: Population-based studies from metropolitan Detroit
CHD8, a novel ATP-dependent chromatin remodeling enzyme
Inducible regulation of gastrin gene expression during Helicobacter pylori infection
Cell specific regulation of sonic hedgehog in adult stomach: Understanding mechanisms leading to gastric atrophy/metaplasia
Origin and evolution of mycorrhizal symbioses in land plants
Flagellin is critical for Legionella motility and macrophage recognition
Structural basis of Vps4 function and regulation in the multivesicular body pathway
Inactivation of YAP-TEAD by the Hippo pathway is involved in growth control and cancer
The role of lipoate dependent metabolism during intracellular growth and pathogenesis of Listeria monocytogenes
Bioinformatic analysis of epithelial:mesenchymal crosstalk during mouse gut development and patterning
The role of Gata2 in hematopoietic and vascular development
Analysis of the molecular mechanism of autophagosome formation in yeast and zebrafish models
Role of beta-catenin signaling in adrenocortical development and tumorigenesis
Metabolic differences in cells from long-lived mice
Analysis of murine mammary epithelial cellular hierarchy
Hox function in mammalian kidney development
Mechanistic studies on AdoCbl-dependent glutamate mutase
Monitoring biological processes and interactions at lipid membranes using ion channel-based sensors and membrane microarrays
Large-scale analysis of filamentous growth in Saccharomyces cerevisiae and the related human fungal pathogen, Candida albicans
Transforming growth factor beta, allograft acceptance and chronic allograft rejection
Regulation of the Huntingtin interacting protein 1 (HIP1) gene
Crosstalk between endothelial cells and tumor cells in head and neck cancer
The role of SEPT9_v1 in breast cancer: Insights into the development of pro-oncogenic phenotypes and genomic instability
Lineage-specific functions of the homeodomain transcription factor Pitx2 in eye development
Bmi1 and Hedgehog signaling in medulloblastoma pathogenesis
Hedgehog-Wnt interactions during pathologic epithelial bud development and skin tumorigenesis
Identification of the outer membrane immunoproteome of the uropathogen Proteus mirabilis: Insights into virulence and potential vaccine candidates
Regulating gene expression through DNA mechanics: Tightly looped DNA represses transcription
Integrative statistical methods for the analysis of transcriptomic and metabolomic data
Effects of in vivo exercise and in vitro contractile activity on the regulation of AS160, TBC1D1 and glucose transport in rat skeletal muscle
Molecular mechanisms of growth hormone-induced signal transduction and SH2B1beta-mediated regulation of the actin cytoskeleton
The cellular roles of the translesion polymerases Eta, REV1 and Zeta in bypass and repair of DNA damage induced by anti-cancer agents
Regulation and role of DAX1 in mouse embryonic stem cells
The SNM1B nuclease plays important roles in maintaining genome stability
Moloney murine leukemia virus RNA recruitment
Multimerization and membrane distribution of the Gag structural polyprotein during HIV-1 assembly
Analysis of chromatin modification and remodeling in the transcriptional regulation of the Wnt/Wg pathway
Tri-lineage differentiation of embryonic stem cells: Role of Wnt signaling
Analysis of the molecular mechanism of autophagosome formation in the yeast Saccharomyces cerevisiae
Regulation of apical polarity complexes
Characterization of mouse models to study protein trafficking in the early secretory pathway
Regulation of Copper Homeostasis by the X-linked Inhibitor of Apoptosis Protein
Evolution of eukaryal tRNA-guanine transglycosylase: Insight gained from the characterization of the human and Escherichia coli tRNA-guanine transglycosylases
Shining Light On Dim2: Dissecting the Roles of an RNA-Binding Protein in Ribosomal Small Subunit Assembly
Mechanisms of melanoma cell survival and maintenance: Targeting apoptosis and autophagy to improve disease treatment
Crystal structures of GfcC, a group 4 capsule operon protein from Escherichia coli, and YraM, an outer membrane lipoprotein from Haemophilus influenzae
Roles of Jak2 in leptin action: From molecular signaling to physiology
Upstream components of mTORC1
Allosteric regulation of Gs on agonist, antagonist and inverse agonist binding to the beta2AR
Contributions to inflammation and sepsis by Inhibitor of Apoptosis proteins
Insights from murine models of neurofibromatosis type I: The etiology and appropriate therapeutic windows for peripheral nerve sheath tumors
Interleukin-10 in the Control of Tumor Immunity and Autoimmunity
Homeostatic roles for adult intestinal hedgehog signaling: Insight into smooth muscle maintenance and inflammatory control
Molecular Architecture of a 40S Ribosomal Subunit Maturation Intermediate
Structural Basis and Functional Consequences of Alternative ATF2-Jun Heterodimer Orientations at the Interferon-beta Enhancer
Endothelial cell-stem cell crosstalk in head and neck cancer
Genetic Diversity, Population Structure, and Virulence Gene Polymorphisms in Nontypeable Haemophilus influenzae
Regulation of bone formation and pathology by local actions of leptin in the bone marrow
The E2F1/DNMT1 axis represses AR in both normal and malignant prostate epithelium
The Glutaredoxin-like Cystein-rich family of genes, Grxcr1 and Grxcr2, in stereocilia development and function
LINE-1 Retrotransposition in Human Genomic Variation
Spatial coordination of tRNA genes
Investigating the role of HIP1/PDGFbetaR in leukemogenesis and imatinib sensitivity
Proinsulin Trafficking through the Secretory Pathway
Targeting Protein Quality Control Pathways in Spinal and Bulbar Muscular Atrophy
Molecular mechanisms of nuclear hormone receptor transcriptional synergy and autoinduction
Investigation of the Formation of Z-DNA and Other Non-Canonical DNA Conformations Using a Combined Spectroscopic and Biochemical Approach
The role of Lgl, aPKC, and Numb in distinguishing neural stem cells from progenitor cells in Drosophila
The effect of tubulin acetylation and detyrosination on the in vitro motility of kinesin-1
Hypochlorous acid stress responses in bacteria
Overlap of cargo adaptor binding sites on myosin V coordinates the inheritance of diverse cargoes
Genetic and Functional Evaluation of Aminoacyl-tRNA Synthetase Mutations in Patients with Peripheral Neuropathy
Mechanobiology of Short DNA Molecules: A Single Molecule Perspective
Xenobiotic-metabolizing enzymes elevated in multiple mouse models of slow aging
Mechanisms and Regulation of Transforming Growth Factor Superfamily Mediated Gene Expression
A novel transcriptional repressor-activator relationship in Growth Hormone-regulated gene expression