ProQuest Subject Index - Pharmaceutical Chemistry at UNIVERSITY OF KANSAS

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You are viewing titles for UNIVERSITY OF KANSAS in the Pharmaceutical Chemistry available through the UMI Dissertations & Thesis Gradwoorks site

Synthesis of seven-membered cyclic sulfamide analogs of DMP 323 and complex N-hydroxy sulfamide scaffolds as potential inhibitors of MMP	Dual labeled TIPP (Tyr-Tic-Phe-Phe, Tic = 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid) peptides as pharmacological tools to study delta opioid receptors

Polyethylene oxide-polyester micelles for drug delivery	Pure insulin nanoparticle agglomerates for pulmonary delivery

Novel intramolecular nucleophilic addition reactions: Formation of unusual N-O-heterocyclic enones	Synthetic and computational efforts toward the understanding and development of novobiocin-derived inhibitors of Hsp90

Kernel functions for graph classification	Design, synthesis and metabolism of arodyn analogs

Natural product inhibitors of Hsp90: Potential leads for drug discovery	Modulators of toll-like receptors-4 and -2

Cocrystallization to improve the dissolution and pharmacokinetics of a poorly soluble drug	Redox modifications of zinc binding proteins

Total synthesis and structure-activity relationship studies of antifungal peptidyl nucleoside antibiotics	Development of fluorescent/stable isotope tagging strategies for proteins containing DOPA

Development of analytical methodologies for the separation and detection of reactive oxygen and nitrogen species	Structure-based design and synthesis of inhibitors of phenylethanolamine N-methyltransferase

Phosphoryloxymethyl/(oxymethyl) prodrugs of beta-dicarbonyl carbon acid drugs	An empirical phase diagram approach to the characterization of therapeutic proteins

Characterization of protein structure in the solid state by H/D exchange with mass spectrometry and its application in lyophilized protein formulation	Applications of nuclear magnetic resonance spectroscopy to pharmaceutical solids

Development of mass labels for the comparative quantitative analysis of 3-nitrotyrosyl proteins	Rational development of protein formulations in solid and solution states

Biophysical characterization of the EC5 domain of E-cadherin: Conformation, physical stability, and binding properties	Physical and chemical properties of boronic acids: Formulation implications

Function and modulation of physical and biological barriers to drug absorption in the rat intestinal mucosa	Targeting both ends of Hsp90: Chimeric N-terminal inhibitors and novobiocin-derivatized C-terminal inhibitors

Improvement of the chemical and physical stability of the EC1 domain of E-cadherin by blocking its disulfide-mediated dimerization	Improving the biopharmaceutical properties of cyclic opioid peptide prodrugs

Improving blood brain barrier permeation of small molecules exhibiting chemotherapeutic and neuroprotective effects	Chemical and physical characterization of therapeutic proteins in solution and amorphous solids

Targeted drug delivery to leukocytes with ICAM-1 derived peptides	A proteomic study of protein tyrosine nitration

Design and synthesis of novel linear and cyclic peptide ligands for kappa opioid receptors	Synthesis and physiochemical characterization of sulfenamide prodrugs of antimicrobial oxazolidinones

Nanoparticle agglomeration via ionic colloidal destabilization as a novel approach to dry powder formulations for pulmonary drug delivery	The Niemann-Pick C1 protein functions in regulating lysosome amine content

Roles of sulfotransferase enzymes in trans-placental disposition	Design, synthesis and evaluation of peptide-based affinity labels for mu opioid receptors

Creating a multivalent subunit vaccine using type III secretion system tip proteins as antigens	Understanding structural stability of pharmaceutically relevant macromolecular complexes: A biophysical and biochemical approach

Development of online microdialysis-microchip system for in vivo monitoring	Using high-resolution NMR to examine the components that contribute to the activity and stability of phosphatase of regenerating liver (PRL-1) and their dependence on the redox state of cysteine residues

Development of analytical methodology for neurochemical investigations	Methods for increasing sensitivity and throughput of solid-state NMR spectroscopy of pharmaceutical solids

Phenanthropiperidine alkaloids: Methodology development, synthesis and biological evaluation