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UNIVERSITY OF DELAWARE
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Development and evaluation of a viable chicken egg assay to determine the metabolic fate of xenobiotic and other teratogenic compounds
Analysis of a flavin sulfhydryl oxidase isolated from bovine milk
Searching for the American eel (Anguilla rostrata) attractant in American horseshoe crab (Limulus polyphemus): The development of a laboratory choice bioassay, biodegradable bait matrix and field trials
Studies of psi synthase RluA with a potent inhibitor: RNA containing 5-fluorouridine
The expression of the High Mobility Group N (HMGN) family of proteins during development of the mouse eye
Study of dynamics in a reaction catalyzed by ht- and ps-ADH: Cloning, purification and preliminary x-ray screening
Refinement, validation, and application of a charge equilibration force field for simulations of phospholipid bilayers
Roles of transmembrane domains in the folding and assembly of the adenosine A2A receptor
Elucidation of sulfur transfer mediated by ThiI
Roles of transmembrane domains in the folding and assembly of the adenosine A2A receptor
Mechanistic studies of flavoenzymes in fatty acid oxidation and oxidative protein folding
Development of novel switchable motifs and new strategies to build functionally privileged structures
Bacillus subtilis and human adenylosuccinate lyase: I. Studies of two novel point mutations of ASL deficiency. II. Effect of adjacent amino acids on the pK of His68. III. Studies with a new substrate analogue
Designing functional materials using the hydrophobic face of a self-assembling amphiphilic beta-hairpin peptide
Overcoming expression obstacles in producing functional components of the G-protein coupled receptor pathway
Heparanase: Expression and function during embryo implantation and modulation of heparanase activity by HIP/RPL29
Mechanism of homologous recombination mediated by human Rad51 protein
Modeling and analysis of the ErbB signaling network: From single cells to tumorigenesis
Exploring the effects of arsenic(III) species on peptides and proteins
Controlled multivalent interactions in the inhibition of toxins via well-designed glycopolypeptides
Human quiescin-sulhydryl oxidase 1b: Role of CxxC motif cysteines in catalysis
SV40 large T antigen helicase: Roles of the hydrophilic channels and a newly identified unwinding activity
In vitro investigations into the structures of membrane-associated proteins augmented by the application of computational methods
Surface-induced peptide folding
Structural enzymology of human senescence marker protein 30 (SMP30): Insights into the gluconolactonase mechanism and role of metal ions
Characterization of two antioxidant enzymes: Paraoxonase-1, and peroxiredoxin-6
Synthesis and reactivity of synthetic analogs for nickel redox enzymes: Superoxide dismutase and acetyl coenzyme A synthase
Light directed gene patterning using photocaged doxycycline
Development of a universal DNA fingerprinting technique using microarray technology
Architecture effects on multivalent interactions by polypeptide-based multivalent ligands
Mechanistic studies of the human recombination proteins RAD51 and RAD54 at the molecular level via fluorescence resonance energy transfer (FRET)
Understanding the structure, dynamics, and mass transport properties of self assembling peptide hydrogels for injectable, drug delivery applications
The design and application of protein kinase-inducible domains as a general approach for detection of kinase and phosphatase activities
Cathodic current enhancement via manganese and oxygen related reactions in marine biofilms
Extracellular matrix protein patterns and gradients to modulate axonal growth
Adenylosuccinate lyases (ASL) from Bacillus subtilis and Homo sapiens: I. Evaluation of types of interactions in the subunit interface II. Studies of five point mutations and mutant ASL hybrids associated with ASL deficiency
Conformational assembly and biological properties of collagen mimetic peptides and their thermally responsive polymer conjugates
Mechanistic studies of the pseudouridine synthases TruB and RluA and their interaction with 5-fluorouridine
Membrane protein purification and characterization of protein-detergent complexes
Post-transcriptional mRNA regulation in neurons and mechanisms of post-transcriptional RNA modification in vitro
Mechanistic insights into the Erv/ALR family of sulfhydryl oxidases
Novel approaches to the expression and purification of G protein-coupled receptors
Characterization of a novel redox active thiol from Chlorobaculum tepidum
Hyaluronic acid-based hydrogel systems for mechanistic studies of prostate cancer metastasis
Revealing cellulose pyrolysis chemistry for biofuels production
Designing injectable beta-hairpin peptide hydrogels for cartilage tissue engineering application
Characterization of the association of human plasma platelet-activating factor acetyl hydrolase with lipoproteins