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You are viewing titles for UNIVERSITY OF CALIFORNIA SAN FRANCISCO in the Molecular biology available through the UMI Dissertations & Thesis Gradwoorks site
 
The consequences of DNA re-replication
Differential requirements of triglyceride synthesis enzymes in the development of hepatic steatosis
 
Identifying the structural determinants of extreme folding and unfolding barriers
S phase inheritance of transcriptional silencing: The role of Sir1 and Asf1
 
The M. tuberculosis ESX-1 secretion pathway modulates the host-pathogen interaction and is regulated through coupling of transcription and secretion
Dgat1 modulates hair cycling and is essential for retinoid homeostasis in the skin
 
Histone H3-K36 methylation antagonizes silencing in Saccharomyces cerevisiae
Regulation of eukaryotic transcription by modification of chromatin structure
 
Regulation of spindle stability by Cdk1 and the APC
Genome-wide analysis of re-replication initiation and elongation in Saccharomyces cerevisiae
 
Biochemical and functional analysis of Ras pathway mutations in myeloid leukemia and developmental disorders
Posttranslational regulation of Cubitus interruptus in Hedgehog signaling in Drosophila
 
3D motifs as signatures of protein function and evolution
Towards an understanding of the gene regulatory network of the intraerythrocytic developmental cycle of Plasmodium falciparum
 
Determinants of glucocorticoid receptor (GR) transcriptional specificity and genomic occupancy
Covalent capture of kinase substrate phosphopeptides for analysis of cellular signaling networks
 
Identification and analysis of negative heterochromatin regulators in Saccharomyces cerevisiae
Investigation into the role of Zn72D and Belle in the regulation of Drosophila dosage compensation
 
Regulation of the Anaphase-Promoting Complex in late mitosis
Elucidating the role of Foggy, a transcription elongation factor, in zebrafish development
 
Functions of yeast Tel2 in genomic integrity
Ordering the pathway of prion propagation in yeast through a structure/function analysis of Hsp104
 
Elucidating the role of Tec1 in the maintenance of signaling specificity in S. cerevisiae
Synaptic trafficking of glutamate receptors by MAGUK scaffolding proteins in the mammalian hippocampus
 
MicroRNA regulation of cardiac development
Genomic study of Plasmodium falciparum gene regulation and mechanisms of drug action and resistance
 
Interrogating the roles of specific downstream effector pathways in the pathogenesis of hematopoietic malignancies initiated by oncogenic K-RasG12D
CDK regulation of replication proteins: Mcm2-7 and DNA polymerase alpha primase
 
The immune paradox of human pregnancy: Fetal trophoblasts and maternal leukocytes
Splicing is regulated in response to environmental changes in yeast
 
The transcription factor MEF2C regulates B cell maturation, proliferation, and function
Systematic identification of regulatory pathways in human and mouse embryonic stem cells and other mammalian systems
 
Combinatorial control of the cell cycle
A correspondence between solution-state dynamics of an individual protein and the sequence and conformational diversity of its family: Implications for improving protein design
 
Genetic and cellular analysis of nerve ring defects in C. elegans
Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans
 
Evolutionary constraints on the structural similarity of proteins and applications to comparative protein structure modeling
Exploring the non-transcriptional activity of thyroid hormone derivatives
 
Identification of the ubiquitin ligase Bre1 and its role in antagonizing gene silencing and promoting mitotic exit
Investigations of 3-iodothyronamine as a novel regulator of thyroid endocrinology
 
Misclocalized scaffolding by the Na-H exchanger NHE1 inhibits fibronectin production and assembly
Understanding signaling specificity in Saccharomyces cerevisiae
 
Structural and biochemical investigations of the thyroid hormone receptor and v-erbA oncoprotein
Role of GABA signaling in circuit formation of the developing cortex
 
Suppression of the DNA damage checkpoint by the Saccharomyces cerevisiae polo-like kinase, CDC5, to promote adaptation
The role of Dicer in post-mitotic dopaminoceptive neurons and turnover of Dicer generated microRNAs
 
Deciphering the melanocortin system: Three distinct approaches
Prion-like characteristics of the microtubule-associated protein tau
 
The role of arc in regulating spine morphology and neural network stability in vivo
Regulation of active zone assembly and function by a newly-identified serine-arginine protein kinase
 
Heterologous expression of human membrane protein drug targets and the X-ray crystallographic determination of the human aquaporin 4 structure
Genetic analysis of TOR complex 2 signaling
 
Molecular architecture of the centriole proteome
E2s act sequentially in the assembly of ubiquitin chains by the anaphase-promoting complex
 
Substrate binding by the anaphase-promoting complex
Multiple signal integration by the glucocorticoid receptor
 
Enzymatic and structural studies of the molecular chaperone Hsp90
The role of SWI/SNF chromatin remodeling in breast tumorigenesis
 
Glucocorticoid receptor DNA occupancy and transcriptional regulation across cell types
The evolution of a transcriptional circuit governing fungal morphology
 
The pathogenic fungus Cryptococcus neoformans and its adaptation to the host environment
Carbohydrate receptors, preterm labor, and periodontitis
 
Spreading the seeds of neurodegeneration: Tau fibrils enter cells by macroendocytosis
Activating events of the unfolded protein response in Saccharomyces cerevisiae
 
Application of the floxin gene targeting technology reveals that Ofd1 controls centriole length
The regulation of pre-mRNA splicing in response to environmental stress in budding yeast
 
Cellular and molecular mechanisms of axonal degeneration in experimental glaucoma
Nucleic acid methods in yeast and infectious disease
 
Using switchable mouse models to assess the therapeutic potential of MdmX and E2F3
Human trophoblast differentiation and invasion during normal pregnancy and preeclampsia
 
Signaling Scaffolds in Cardiovascular Development and Disease
Participation of Regulatory Factors and the Coregulator Brm in the Combinatorial Control of Transcription
 
The role of integrin alpha9beta1 during angiogenesis induced by VEGF-A
Dimerization of Telomerase RNA During Telomerase Biogenesis Regulates Telomerase Activity
 
Studies of the Carcinoma-Associated Fibroblast in Human Oral Squamous Cell Carcinoma
Conformational control of eukaryotic mRNA decapping by Dcp2
 
On RNA 3'-end Oligouridylation
The Role of Polycomb-like 3 and Ofd1 in Embryonic Stem Cell Maintenance and Differentiation
 
Synthetic Logic Circuits in Escherichia coli
Virus-host Cophylogeny Motivated Viral Detection and Discovery Using Viral Microarrays and High-throughput Sequencing
 
Closing the gaps and pushing the boundaries: Understanding the mechanism and regulation of heterochromatin-induced transcriptional silencing
Refactoring the Salmonella type III secretion system
 
Manipulating developmental mechanisms to promote remyelination
The Semi-Explicit Assembly Solvation Approach and Selected Applications
 
Eri1 Regulation of Lymphocyte MicroRNA Homeostasis and Effector Functions
Activation of Apoptotic Procaspases
 
Stage-specific Chromatin Modification and Regulation in Cardiomyocyte Differentiation
The Molecular Mechanisms of Transcriptional Regulatory Network Divergence
 
RNA Regulation During the Unfolded Protein Response in Yeast
Molecular Control of a Cell Cycle Event
 
Analysis of the Initiation, Progression, and Therapy of BRAF(V600E) and KRAS(G12D) - driven Non-Small Cell Lung Adenocarcinoma Using Conditional Mouse Models
Determinants of Recombination in RNA viruses
 
Regulation of the development of pancreatic diseases by cell intrinsic and stromal influences
Investigation into the mechanisms underlying activation-induced microRNA and Argonautc downrcgulation in helper T cells
 
MicroRNAs Promote Induced Pluripotency Through the Regulation of Cooperative Gene Networks
Regulation of transcription in pathogens, yeast and people
 
Characterization of Jumonji demethylase activity on peptides and nucleosomes
Investigating the effects of ADP-ribosylation factor 4 (Arf4) on pattern separation and dendritic spine development