ProQuest Subject Index - Biochemistry at UNIVERSITY OF CALIFORNIA SAN FRANCISCO

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You are viewing titles for UNIVERSITY OF CALIFORNIA SAN FRANCISCO in the Biochemistry available through the UMI Dissertations & Thesis Gradwoorks site

Towards membrane protein structure determination	The detection, prevalence and properties of aggregate-based small molecule inhibition

Construction of synthetic signaling circuits by modular recombination	Identification and characterization of microtubule assembly factors

Regulation of spindle stability by Cdk1 and the APC	Small molecule modulation of protein secretion

Chemical and structural components of specific RNA recognition	Cysteine protease function in Trypanosoma brucei

Covalent capture of kinase substrate phosphopeptides for analysis of cellular signaling networks	Structure and assembly properties of a conserved C-terminal domain in Kv7 channels

Rewiring the regulatory mechanisms of signaling proteins	Analysis of superfamily catalytic modules for applications in protein and pathway engineering

Ordering the pathway of prion propagation in yeast through a structure/function analysis of Hsp104	MicroRNA regulation of cardiac development

Matrix attachment therapy for cancer	Dual-specificity inhibitors of lipid and protein kinases

Conformational switches regulate clathrin mediated endocytosis	Development and application of technologies to study individual kinase substrate relationships

The description, prediction and misprediction of protein function	A yeast screen for PI3K inhibitor resistance

The pursuit of membrane protein structures and the malarial aquaglyceroporin pfAQP	Protein interactions mediating endocytic recycling of G protein-coupled receptors

Investigations of 3-iodothyronamine as a novel regulator of thyroid endocrinology	Understanding signaling specificity in Saccharomyces cerevisiae

Structural and biochemical investigations of the thyroid hormone receptor and v-erbA oncoprotein	Solution structures and conformational dynamics of the molecular chaperone Hsp90

The structural and functional landscape of protein superfamilies: From the thioredoxin fold to parasite peptidases	Active-site inhibition of the mammalian Target of Rapamycin

Electrophilic nucleosides: Tools to explore protein kinases	E2s act sequentially in the assembly of ubiquitin chains by the anaphase-promoting complex

Substrate binding by the anaphase-promoting complex	The structural bases of stability-function tradeoffs inantibiotic resistance enzymes

Discovery of novel inhibitors of ornithine decarboxylase in Trypanosoma brucei: Development and application of a targeted high-throughput screening program	Structural determinants of protein dynamics, cooperativity and kinetic stability in alpha-lytic protease

The evolution of a transcriptional circuit governing fungal morphology	Activating events of the unfolded protein response in Saccharomyces cerevisiae

Activation of specific apoptotic caspases with an engineered small-molecule-activated protease	Development of cell-active irreversible inhibitors of the human centrosomal kinase Nek2

In vitro studies of Steriodogenic Factor-1 sumoylation, a post-translational modification critical for adrenal and gonadal development	Mechanistic analyses of the heterochromatin proteins MacroH2A and HP1

Participation of Regulatory Factors and the Coregulator Brm in the Combinatorial Control of Transcription	Regulation of Flagellar Length by Intraflagellar Transport

Dimerization of Telomerase RNA During Telomerase Biogenesis Regulates Telomerase Activity	Conformational control of eukaryotic mRNA decapping by Dcp2

Function of macromolecular serine protease inhibitors in the human blood fluke Schistosoma mansoni	WAVE-mediated Actin Assembly

Dissecting biological pathways in cancer and bacteria through the study and application of serine protease inhibitors	Development of Allosteric Inhibitors Targeting Human Herpesviral Proteases

On RNA 3'-end Oligouridylation	Analysis of the Nucleophilic Attack 6-bladed beta-Propeller Superfamily Provides Insight into the Evolution of Function in Strictosidine Synthase-like Proteins

Characterization of the role of cercarial elastase in schistosome host invasion and immune evasion	Molecular mechanism of cotransin action

The Effect of Lipid Chemistry and Structure on Liposome Formation	Evolutionary Conservation of Apoptotic Caspase Substrates

Ligand Desolvation in Molecular Docking (How, Why, and With What?)	Activation of Apoptotic Procaspases

Primary cilia as signaling organelles in development and disease	Biophysical Characterization Studies of the Mercury Resistance Proteins MerT and MerA

Molecular Control of a Cell Cycle Event	Analysis of the Initiation, Progression, and Therapy of BRAF(V600E) and KRAS(G12D) - driven Non-Small Cell Lung Adenocarcinoma Using Conditional Mouse Models

Integrating protein similarity networks and orthogonal information for understanding protein origins and function	Characterization of Jumonji demethylase activity on peptides and nucleosomes

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles	Microfluidic Frameworks for Immunoanalysis of Multiple Proteins

Regulation of HIV Vif by host factors