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You are viewing titles for UNIVERSITY OF CALIFORNIA LOS ANGELES in the Molecular biology available through the UMI Dissertations & Thesis Gradwoorks site
 
Prolonged alpha-amanitin treatment of cells for studying mutated polymerases causes degradation of DSIF 160 and other proteins
Applying ESI-GEMMA towards the Study of Large Protein Complexes
 
Profiling changes in glycosylation during C2C12 myoblast differentiation
TNFalpha enhances cancer stem cell-like phenotype via Notch-Hes1 activation in oral squamous cell carcinoma cells
 
Cyclophilin A Regulates Osteogenesis via NF-kappaB/p65 Through Direct Interaction
Molecular mechanisms of TLR4- and Nod2-mediated innate immune responses
 
Using mouse models to study paraoxonase 3 and other candidate genes in atherosclerosis and infection
Characterization and utilization of simple replication-competent retroviral vectors
 
Type I IFN dependent and independent mechanisms of gene regulation: Implications in autoimmunity and drug metabolism
Novel dioxin-regulated genes and their associated biological effects
 
A novel pooling-deconvolution strategy for biological network elucidation
Identification of the Nipah virus receptors: Insight into the pathogenesis of Henipavirus infection
 
The oxidative stress response in Drosophila: A developmental and molecular genetic analysis
Uncovering targets of superoxide in the budding yeast Saccharomyces cerevisiae
 
Brain iron accumulation in Parkinson's disease: An investigation of genes related to iron metabolism and homeostasis and dietary behavior data in a case-control study of residents in the central California tri-county area
Topological complexity in models of protein folding, stability and design
 
Mitochondrial import of the small TIM family of proteins in Saccharomyces cerevisiae and Caenorhabditis elegans
Novel functions and interactions of the signal transduction protein SOCS3 and its relation to cancer
 
Understanding the molecular determinants of prostate tumorigenesis: Androgen receptor's requirement for histone deacetylases and the role of recurrent ETS fusion
Molecular imaging of gene expression at the level of RNA in living animals
 
Structural and functional studies of IsdH, the hemoglobin and haptoglobin receptor of Staphylococcus aureus
A novel adenovirus-Epstein-Barr virus hybrid vector system for gene transfer
 
The role of lipophosphoglycan in the pathogenesis of Trichomonas vaginalis infection
The innate immune response to human immunodeficiency virus-1 infection of the human thymus
 
Towards a structural understanding of progression and transmission of prion diseases
Structural characterization of amyloid-like protein segments and the rational design of peptide inhibitors of fibrillation
 
Role of transcription factor E4bp4 in glucocorticoid-mediated gene regulation in osteoblasts
Regulation of local signaling by type 2C protein phosphatases
 
The Drosophila Dscam gene encodes a vast repertoire of neuronal recognition molecules
Intrinsic factors influencing protein structure, folding, and complexation studied by ion mobility and mass spectrometry
 
Examining the role of LXRs in lipid metabolism and inflammation
Preclinical evaluation of adenovirus-mediated suicide gene therapy for prostate cancer and multimodality imaging of viral biodistribution and transgene expression
 
Investigating the role of Polycomb Group protein EZH2 in prostate cancer initiation and progression
The biology of the C-type lectin receptor DC-SIGN
 
Influenza-induced type I interferons sensitize hosts to secondary pneumococcal pneumonia
Biochemical and biophysical characterization of the protein import pathway of the mitochondrion
 
Investigating the role of Medicago sativa lectin 1 (MsLec1) in the Sinorhizobium meliloti symbiotic association with plant roots
The roles of SUMO in fly development
 
Pioneer factors mark enhancers for typical tissue-specific genes in pluripotent stem cells
Integration of BMP, RTK/MAPK and Wnt/GSK3 signals through Smad1 phosphorylations
 
Investigations of the central oscillator of the Arabidopsis circadian clock
Zebrafish (Danio rerio) as a model system for human leukemia and hematopoiesis
 
Investigation of Arabidopsis cryptochrome function and localization
Characterization and modulation of transmembrane domain interactions in membrane protein drug-targets
 
The regulation of type I interferon responses to pathogen recognition receptor pathways by TANK-binding kinase-1
The effect of coenzyme Q10 supplementation on aging and disease
 
Galectin-1: Effects on development and function of CD4+ T helper cells
The associations between diet, flavonoids, polymorphisms of the PPAR-gamma, PPAR-delta, and CRP genes and lung and upper aerodigestive tract (UADT) cancers
 
Insights into the pathogenesis of Ewing's sarcoma
RIN1 activates ABL oncoproteins and is required for full BCR-ABL1 mediated transformation
 
A catalytic switch in p300 regulates preinitiation complex assembly
Probing dynamics of ERBB3 receptor signaling with an RNA aptamer
 
Trichomonas vaginalis genome annotation validation and protein function prediction via proteomics and phylogenetics
Development of the nervous system in Aurelia (Cnidaria, Scyphozoa)
 
TNFalpha-mediated endothelial cell apoptosis
Fine mapping of regulatory loci for mammalian gene expression via induced DNA copy number variation in radiation hybrids
 
The mitochondrial import pathways of Taz1p and PNPase
Disruption of the furin cleavage site in mouse Notch1 results in cardiovascular malformations due to hypomorphic Notch1 signaling
 
Molecular basis of the metastatic phenotype of inflammatory breast cancer
Structural studies and drug discovery of the Staphylococcus aureus sortase A enzyme
 
The ever expanding role of Hsp90-Cdc37 chaperone complex in cell signaling networks
The role of mitogen activated protein kinase activated protein kinase-2 in regulating p38 mitogen activated protein kinase induced cyclooxygenase-2 induction and heart failure
 
Exploration of the RNase III dependent nuclear processing and degradation mechanisms of RNA in Saccharomyces cerevisiae
The development of a tumor specific gene therapy vector for the treatment and diagnosis of metastatic breast cancer
 
Investigation of the role of monooxygenases in coenzyme Q biosynthesis
Identification of novel functions for the ATP binding cassette transporters G1 and G4 during development and ageing
 
Differential regulation of PTH-induced primary response gene expression in osteoblasts
PTH and Nurr1 mediated gene expression in osteoblasts
 
Engineered biosynthesis of bacterial aromatic polyketides
Biosynthesis of iterative fungal polyketide synthases in heterologous hosts
 
A multi-lineage based analysis of neural morphogenesis in Drosophila melanogaster
Genetic analysis of cardiac patterning in zebrafish
 
Notch signaling in vascular development: The roles of Notch1 and Jagged1 in vessel morphogenesis and disease
Three daughters of NG2: Lineage tracing of NG2+ progenitors using a transgenic mouse model
 
The Nrf2/ARE pathway influences intrinsic radiosensitivity and is activated by exposure to ionizing radiation
The role of the homeobox gene Hhex in definitive hematopoietic progenitor proliferation and differentiation
 
Characterization of SipW as a bifunctional signal peptidase and its role in biofilm formation by Bacillus subtilis
Identification and characterization of novel core promoter elements and a new transcription factor in Trichomonas vaginalis
 
Characterization of host-pathogen interaction of two bacterial toxins: Anthrax edema toxin and Escherichia coli cytolethal distending toxin
Improving recombinant membrane protein overexpression in E. coli
 
Hematopoietic stem cell development in placental vasculature
RIN1 is a breast tumor suppressor and regulator of EGFR trafficking and signaling
 
Mechanisms of CMT3 activation and histone methylation in Arabidopsis thaliana
Metabolic engineering and modeling for the production of higher alcohols in Escherichia coli
 
Study of the role of activin receptor like kinase-1 signaling in control of vascular endothelial growth factor expression and atherosclerosis
Connective tissue growth factor: Gene regulation and function of CTGF
 
Forces that stabilize membrane proteins
Identification of X11 as a regulator of APP's intracellular domain and axonal protein asymmetry in Drosophila
 
Context-dependent VEGF signaling: Molecular regulation of vascular patterning during angiogenesis
Galectin-1 interactions with N- and O-glycans are dependent on physical characteristics of galectin linkers and presentation of glycan ligands
 
Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor in solid tumors
The transcriptional regulation by neurogenin1 in neurogenesis
 
Functional analysis of iron-deficient Chlamydomonas: Ironing out photosynthesis generates new wrinkles
Identification of cis-regulatory sequences that activate transcription in the suspensor of plant embryos
 
The role of Wnt10b in post natal bone homeostasis and maintenance of mesenchymal progenitor cells
Identification of protein-ligand binding sites by top-down mass spectrometry
 
The identification and functional characterization of rhoptry neck proteins in moving junction formation during invasion by Toxoplasma gondii
The role of glycerol kinase in adipogenesis
 
Programmed cell death-1 ligation: A novel signal regulating development and apoptosis of retinal ganglion cells
A study of coevolved, cofolding and functionally linked proteins and the characterization of amyloid-like fibrils and oligomers towards the understanding of protein aggregation in disease
 
A protein kinase activity radio assay using an integrated microfluidic and solid state beta camera platform
Functional genomics approaches to characterize abnormal cell signaling in cancer
 
Identification of a link between prostate stem cell self-renewal and carcinogenesis
Enhancing the expression of Na,K-ATPase beta1-subunit as a mechanism to suppress carcinoma progression
 
Eukaryotic Methylation: The identification of novel enzyme-substrate pairs
Hin-Catalyzed Inversion
 
Transcriptional Regulation of the Human TGF-beta1 Gene by the GLI Transcription Factors
Transcriptional Regulation of B Cell Development by CRTC2
 
Proteins that Regulate Mitochondrial Fusion, Fission, and Diameter
Zebrafish usp39 mutation leads to rb1 mRNA splicing defect and pituitary lineage expansion
 
Studies on the Physiological Role of Paraoxonase 2 in Inflammatory Diseases
Centromere Protein A Dynamics in Human Pluripotent Stem Cell Self-Renewal, Differentiation and DNA Damage
 
From Yeast to Humans: Uncovering the Methyltransferasome
The Recognition and Depletion of Age-Damaged (R,S)- AdoMet by Homocysteine Methyltransferases
 
Genome-wide function of the Saccharomyces cerevisiae HMGB protein Nhp6A
Synthetic Symmetrization of Proteins for Crystals and Other Assemblies
 
Retinal Ganglion Cell Survival and Immune Response in the Thy1-CFP DBA/2J Mouse Line Following Ocular Injury
IL-1beta downregulates E-cadherin in non-small cell lung cancer via Fra-1 activation
 
Characterizing MEKK1 Activation in Apoptosis by Anti-Cancer Drugs
The role of beta1 integrin in vascular and visceral smooth muscle
 
Structure/Function Analysis Reveals Unexpected Regulatory Roles for the Unconserved Central Region of the Drosophila Corepressor Groucho
Accurate Identification of Internal Ribosome Entry Site and Promoter Sequences
 
The Multiple Roles of EWS/FLI1 in Regulation of Gene Expression
A role for stem/progenitor cells in the initiation of epithelial cancers
 
Structural Studies of Amyloid-Forming Proteins and Peptides
Toxoplasma gondii Rhoptry Effector Proteins: Hijacking the Host Cell
 
Molecular Characterization of PilA And Detailed Understanding of TFP Function in Social Motility in Myxococcus xanthus
Characterization of Protein Arginine Methyltransferases: An Emerging Family of Regulatory Proteins
 
Characterization of the Biosynthetic Pathway of Anticancer Tetracycline SF2575
The Role of MicroRNAs in the Pathogenesis of AIDS-related non-Hodgkin's Lymphomas
 
Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling
Virus and Host Interactions During Murine Gammaherpesvirus 68 Infection
 
Molecular Characterization of Endothelial Cell Targets of HLA Class I-Mediated Antibody Mediated Rejection
Mechanisms of Selective Gene Activation by the NF-kappaB Family of Transcription Factors
 
Toxoplasma gondii employs secreted metalloproteases for host cell invasion and intracellular survival
Mechanisms of Active Sugar Transport in the Kidney: Biophysical Characterization of Human Sodium/D-glucose Co-Transporters, hSGLT1 and hSGLT2
 
Investigation of the Maturation of Yeast Superoxide Dismutase: Effect of the Copper Chaperone, the Disulfide Bond, and Metal Binding
Induction of Pancreatic Beta Cells in Zebrafish
 
Nanorheology of Biological Macromolecules
Molecular Events in the Reacquisition of Pluripotency
 
A High-throughput Screening Approach Identifies Selective Regulators of Il12b Transcription
Molecular and Genetic Study of Human Liposarcoma
 
Discovery and characterization of human exonic transcriptional regulatory elements
The Genetics of de novo Methylation in Arabidopsis thaliana
 
Kinase and Hormone Receptor Signaling Networks in Cancer
Molecular Basis of Coupling 3'-end Processing to Transcription in Mammals
 
Identification of new RNA substrates for the NMD and exosome RNA surveillance pathways in Saccharomyces cerevisiae
Activity-dependent CRTC1 signaling during long-lasting synaptic plasticity
 
Splicing of constitutive and alternative exons during transcription in the mammalian system
Activation of the Retina's Regenerative Potential By Embryonic Stem Cell-Derived Microvesicles
 
Novel Chemical Biology Approaches to Studying Protein Geranylgeranylation
Protein phosphorylation and dephosphorylation during development
 
Coordination of histone H3 Lysine 4 trimethylation-mediated transcription stimulation with Pre-initiation complex assembly
Assessing the Effects of a Coenzyme Q Deficient E. coli Diet in Wild-type Caenorhabditis elegans and coq-3 Gene Mutant C. elegans: Applications for Mitochondrial Disorder Studies and Probiotics
 
Characterization of Cellular Signaling in Ewing Sarcoma Family of Tumors
Determination of Cellular Pathways that Lead to Spontaneous and Induced Mutagenesis in Escherichia coli
 
Identification and characterization of regulators of survival in human pluripotent stem cells
Identification of Novel Cellular Responses to Metal Homeostasis in Saccharomyces cerevisiae
 
Somatosensory Neuron Subtypes and Sensory Transduction in Larval Zebrafish
RNAi High Throughput Screenings Facilitate the Identification of Proteins Necessary for TCDD-induced CYP1A1 Enzymatic Activity and Aid in the Discovery of a Novel Role for Sin3A in AHR-Mediated Gene Expression
 
Functional Characterization of Kansl2 and Its Role in Mitochondrial DNA Repair and Maintenance
RIN3 negatively regulates SCF-mediated responses of mast cells
 
Studying Nucleosome Positioning, DNA Methylation, and Other Epigenetic Factors Using Genomic Approaches
Adenovirus: A Versatile Tool for Studying and Treating Diseases
 
Novel Regulatory Mechanisms of Adipogenesis: Discovery of Vestigial-like 3 (Vgll3)
Recognition of Tetraloop Hairpin RNA by the Double-Stranded RNA--Binding Domain of S. cerevisiae RNase III
 
Investigating the Function of the Preinitiation Complex and the Consequences of Chromatin Modifications
The Role of Heat-Shock Proteins in Production of Infectious Hepatitis C Viral Particles
 
Zinc Finger Nucleases for Site-Specific Correction of Adenosine Deaminase Deficiency