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UNIVERSITY OF CALIFORNIA LOS ANGELES
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You are viewing titles for UNIVERSITY OF CALIFORNIA LOS ANGELES in the Biochemistry available through the UMI Dissertations & Thesis Gradwoorks site
Prolonged alpha-amanitin treatment of cells for studying mutated polymerases causes degradation of DSIF 160 and other proteins
Applying ESI-GEMMA towards the Study of Large Protein Complexes
Dynamics of the L-fucose/H+ symporter revealed by fluorescence spectroscopy
Environmental stress response of protein repair L-isoaspartyl methyltransferase and its physiological role in repairing age-damaged proteins in higher plants
RIN1 is a breast tumor suppressor and is also a component of a breast tumor suppressor locus (B3GNT1-BRMS1-RIN1)
Uncovering targets of superoxide in the budding yeast Saccharomyces cerevisiae
Hydrogen/deuterium exchange studies on copper-zinc superoxide dismutase
Topological complexity in models of protein folding, stability and design
Mitochondrial import of the small TIM family of proteins in Saccharomyces cerevisiae and Caenorhabditis elegans
Structural and functional studies of IsdH, the hemoglobin and haptoglobin receptor of Staphylococcus aureus
Towards a structural understanding of progression and transmission of prion diseases
Structural characterization of amyloid-like protein segments and the rational design of peptide inhibitors of fibrillation
The Drosophila Dscam gene encodes a vast repertoire of neuronal recognition molecules
Lactic acid metabolism in the 18 day old suckling rat
Intrinsic factors influencing protein structure, folding, and complexation studied by ion mobility and mass spectrometry
Computational design of new enzyme catalysts and investigations of biological catalysis and binding
Biochemical and biophysical characterization of the protein import pathway of the mitochondrion
Biological links between cofactors: Metabolism, signaling and dynamic relationships between iron, manganese, and chlorophyll in the green alga Chlamydomonas reinhardtii
Characterization and modulation of transmembrane domain interactions in membrane protein drug-targets
Biochemical and structural insight into the ribonucleoprotein assembly necessary for mobilization of the LINE-1 retrotransposon
Viral encapsulation of emulsion and nanoemulsion droplets
The effect of coenzyme Q10 supplementation on aging and disease
Regulation of activation and maturation of ERBB receptors
Probing dynamics of ERBB3 receptor signaling with an RNA aptamer
Engineering an all human component Antibody Enzyme Prodrug Therapy (ADEPT) to overcome its current clinical limitations
Characterization of roles for the disintegrin and metalloproteases, kuzbanian and tumor necrosis factor-alpha converting enzyme, in mammalian Notch signaling
Biomolecular nanopatterning and single molecule detection
Investigations into cellular metabolism in yeast lacking copper zinc superoxide dismutase
Isoprenoid ether lipid biosynthesis in the extremophile, Archaeoglobus fulgidus
The mitochondrial import pathways of Taz1p and PNPase
Structural studies and drug discovery of the Staphylococcus aureus sortase A enzyme
Exploration of the RNase III dependent nuclear processing and degradation mechanisms of RNA in Saccharomyces cerevisiae
Investigation of the role of monooxygenases in coenzyme Q biosynthesis
Engineered biosynthesis of bacterial aromatic polyketides
Mechanistic analysis of the redox dependent import of proteins into the mitochondrial intermembrane space
Proteomic profiling of saliva for the detection of cancer
Heterogeneities in the 20S proteasome complexes: Molecular organization, assembly and function
Investigation of macromolecular assembly in bacterial microcompartments
A functional analysis of the corepressor Groucho in the development of Drosophila melanogaster
Improving recombinant membrane protein overexpression in E. coli
Electrospray-assisted laser desorption ionization mass spectrometry for proteomic studies
RIN1 is a breast tumor suppressor and regulator of EGFR trafficking and signaling
Design, synthesis and docking models of estrogen and androgen receptor antagonists
The association of the nuclear import factor importin alpha with the NMDA glutamate receptor
Forces that stabilize membrane proteins
Computational biophysical studies of protein crystallization and aggregation
Functional analysis of iron-deficient Chlamydomonas: Ironing out photosynthesis generates new wrinkles
Elucidating the role of mutant human copper-zinc superoxide dismutase aggregates and metal ions in a mouse model of amyotrophic lateral sclerosis
Development of a steric trap method to study water soluble and membrane protein folding
Identification of protein-ligand binding sites by top-down mass spectrometry
The role of glycerol kinase in adipogenesis
A study of coevolved, cofolding and functionally linked proteins and the characterization of amyloid-like fibrils and oligomers towards the understanding of protein aggregation in disease
The physics of DNA, RNA, and RNA-like polymers
Eukaryotic Methylation: The identification of novel enzyme-substrate pairs
Chemical Genetic Dissection of TOR Signaling Through Identification and Characterization of Small Molecule Enhancers of Rapamycin
Hin-Catalyzed Inversion
Understanding the Mechanism of Dscam Mediated Contact Dependent Repulsion
Epigenetic Regulation in Neurological Disorders
Investigating the Differences in Subcellular Protection Against Oxidative Stress in Saccharomyces cerevisiae
Carbon Nanotubes as Biosensors to Detect and Measure Protein Activities Embedded within Lipid Membranes
Proteins that Regulate Mitochondrial Fusion, Fission, and Diameter
Affinity Isolation and Characterization of Mouse High Density Lipoprotein
Structural Studies of the Propanediol-Utilizing Microcompartment of Salmonella enterica
From Yeast to Humans: Uncovering the Methyltransferasome
The Recognition and Depletion of Age-Damaged (R,S)- AdoMet by Homocysteine Methyltransferases
The Sensory Basis for Ecological Paradigms on Wave-Swept Shores
Synthetic Symmetrization of Proteins for Crystals and Other Assemblies
Structural and Functional studies of the Sarcolemmal NA +/Ca2+ Exchanger
A Sweet Tale from the Outer Surface of the Archaea Methanosarcina acetivorans and Methanosarcina mazei
Structural Studies of Amyloid-Forming Proteins and Peptides
Molecular Characterization of PilA And Detailed Understanding of TFP Function in Social Motility in Myxococcus xanthus
Characterization of Protein Arginine Methyltransferases: An Emerging Family of Regulatory Proteins
Characterization of the Biosynthetic Pathway of Anticancer Tetracycline SF2575
Biosynthesis of Fungal Resorcylic Acid Macrolactones
Mass Spectrometry-Based Structural Probing of Amyloid beta-Protein
Mapping molecular flexibility of spin labeled proteins on the nanosecond and longer time scales via CW lineshape analysis and osmolyte-perturbation EPR
Investigation of the Maturation of Yeast Superoxide Dismutase: Effect of the Copper Chaperone, the Disulfide Bond, and Metal Binding
Molecular Events in the Reacquisition of Pluripotency
Highly Active Yeast MnSOD has a Novel Mechanism Involving Six-coordinate Mn(3+) Species
Molecular Basis of Coupling 3'-end Processing to Transcription in Mammals
Identification of new RNA substrates for the NMD and exosome RNA surveillance pathways in Saccharomyces cerevisiae
Biomimetic Synthesis of Noble Metal Nanoparticles and Their Applications as Electro-catalysts in Fuel Cells
Splicing of constitutive and alternative exons during transcription in the mammalian system
Novel Chemical Biology Approaches to Studying Protein Geranylgeranylation
Isoreticular Expansion of Metal-Organic Frameworks with Multiple Functionalities and Controlled Pore Sizes
Protein phosphorylation and dephosphorylation during development
Enhancing the Detection of Biomolecules Using Aqueous Two-Micellar Systems
Coordination of histone H3 Lysine 4 trimethylation-mediated transcription stimulation with Pre-initiation complex assembly
Single Molecule Science for Personalized Nanomedicine: Atomic Force Microscopy of Biopolymer-Protein Interactions
Computational methods for analysis and redesign of enzyme active sites
Structural characterization of prions: Two-sheet and three-sheet steric zipper models of the polymorphic prion aggregate
Synthesis and Biological Testing of Glycosylated Fluoroquinolone Antibiotics
Spectroscopic studies on chemical- and photo-responsive molecular machines and their bio-applications
Identification of Novel Cellular Responses to Metal Homeostasis in Saccharomyces cerevisiae
Single Molecule Spectroscopy for Studying Conformational Dynamics of Short Oligonucleotides
Functional Characterization of Kansl2 and Its Role in Mitochondrial DNA Repair and Maintenance
Synthesis of the Tricyclic Core of Guanacastepene A, Decarboxylative Rearrangement of Allenylic N-Tosyl Carbamates and Phosphine-catalyzed Intramolecular gamma-Umpolung Addition of alpha-Aminoalkylallenic Esters, and the Enantioselective Total Synthesis of (+)-Ibophyllidine
Investigating the Function of the Preinitiation Complex and the Consequences of Chromatin Modifications