ProQuest Subject Index - Pharmaceutical sciences at THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

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You are viewing titles for THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL in the Pharmaceutical sciences available through the UMI Dissertations & Thesis Gradwoorks site

Features associated with diet pill use in individuals with eating disorders	Combined gene therapy of siRNA and apoptosis inducing factor generated from a single transcriptional event

Protein function prediction using family-specific structural motifs	Quantitative structure-toxicity relationship modeling of organic compounds and nanoparticles

Effect of prescription copayments on medication compliance and hospitalizations in commercially insured patients with heart failure	Prediction of brain extracellular fluid concentrations: Application to understanding central nervous system pharmacokinetics and pharmacodynamics

Impact of medication stressors on emotional health of informal caregivers of demented patients	Novel dry powder preparations of whole inactivated influenza virus for nasal vaccination

The evolution of antibacterial chemotherapy: Targeting RecA to sabotage antibiotic tolerance and resistance mechanisms	Innovative biomedical applications using hybrid nanoparticles

Parametric and non-parametric approaches to quantitating pharmacodynamic response	Towards de novo synthesis of structure-defined oligosaccharides with heparan sulfate biosynthetic enzymes

Role of basolateral efflux transporters in intestinal absorption of drugs and prodrugs	The effects of non-steroidal anti-inflammatory drugs (NSAIDs) on blood pressure in patients with hypertension

Cost as a feature of medication management communication in medical visits	Utility of two distinct macromolecular carriers for nucleic acid delivery

The Orphan Drug Act of 1983: A case study of issue framing and the failure to effect policy change from 1990--1994	Investigation of electrostatic charging phenomena in dry powder inhalers and the effect on deposition

Antibody carriers of CpG oligodeoxynucleotides for solid tumor immunotherapy	An investigation into the role of glucuronidation on the disposition and toxicity of mycophenolic acid using targeted quantitative proteomics

Investigation of probe substrates to assess hepatic transport function	Classifier design to improve pattern classification and knowledge discovery for imbalanced datasets

An ex vivo familial genetics strategy for determining mechanism of action	A novel mechanism for intestinal absorption of the type II diabetes drug metformin: Role of cation-selective apical transporters in paracellular absorption

Nanoparticle delivery of siRNA for cancer therapy	Diagnosis and treatment of pediatric bipolar disorder in a commercially insured population

The effect of patient race on patient-provider communication with pediatric asthma patients	A chemical biology approach to discover the biological targets of the antiepileptic drug lacosamide

Heterogeneous particle deaggregation and its implication for therapeutic aerosol performance	A localized, quantitative drug delivery tool for neurotransmission studies

Design, synthesis, and structure-activity relationship investigation of 3',4'-disubstituted pyranochromone derivatives with diverse biological activities	Cheminformatics Approaches to Structure Based Virtual Screening: Methodology Development and Applications

Synthesis and pharmacological evaluation of primary amino acid derivatives (PAADs): Novel neurological agents for the treatment of epilepsy and neuropathic pain	Paclitaxel-2'-O-pentadecylhemiglutarate: A Prodrug Strategy for Albumin Based Drug Delivery

Development and Extension of Cheminformatics Techniques for Integration of Diverse Data to Enhance Drug Discovery	Enhancing drug safety through active surveillance of observational healthcare data

The effect of the dynamic interplay of P-glycoprotein and cytochrome P450 3A on the portal bioavailability of dual substrates	Detection and Mechanistic Comparison of Two Anti- Trypanosomal Diamidines in a Rat Renal Model

Segregation of the biological functions of heparan sulfate	Cheminformatics modeling of diverse and disparate biological data and the use of models to discover novel bioactive molecules

Prioritizing Small Molecules for Drug Discovery or Chemical Safety Assessments using Ligand- and Structure-based Cheminformatics Approaches	Cytochrome P450-derived eicosanoids, inflammation, and atherosclerotic cardiovascular disease

Pre-clinical assessment of genetic and neurobiochemical markers for depressive behavior and antidepressant response	Lipid-based cancer vaccines

The QSARome of the receptorome: Quantitative structure-activity relationship modeling of multiple ligand sets acting at multiple receptors	Development and application of cheminformatics approaches to facilitate drug discovery and environmental toxicity assessment

DDB and betulinic acid-derivatives as potent chemosensitizing, chemopreventive, and anti-HIV agents	Implications of the shape of telomerase RNA

Interactions of antiretroviral protease inhibitors with hepatic transport proteins: Mechanisms of drug-induced liver injury	Drug-Loaded Lipid Nanoparticles for Improved Cancer Treatment: Engineering, In-Vitro, and In-Vivo Evaluation

Develop Small Molecule Regulators of GTPase-activating Proteins of ADPribosylation Factors (ARFGAPs)	Defining the structural cues within heparan sulfate that direct heparanase cleavage

The participation of pregnant women in clinical research: Implications for practice within the U.S. pharmaceutical industry