ProQuest Subject Index - Pharmaceutical Chemistry at THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

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You are viewing titles for THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL in the Pharmaceutical Chemistry available through the UMI Dissertations & Thesis Gradwoorks site

Evaluation of potential inhibitors of Escherichia coli RecA to attenuate the rate of antibiotic resistance development and to sensitize Escherichia coli to current antibiotics	Novel approaches to assess the efficacy and toxicity of intestinal absorption enhancers

Mechanisms of ligand-receptor interactions of the dopamine D2L receptor and their relation to functional selectivity	Polymeric nanogels as gene carriers

Static and dynamic insights into the function of the human nuclear xenobiotic receptor PXR	Aerosol delivery of recombinant antigen 85B in microparticle vaccine systems for protection against tuberculosis

Interrogation of telomerase structure and function with telomeric DNA	A mechanism of resistance and mode of action for drugs against Plasmodium falciparum

Synthesis and characterization of dendrimer-based nitric oxide delivery systems	Structure and function of Tetrahymena thermophila telomerase RNA

Innovative biomedical applications using hybrid nanoparticles	Design, synthesis, and biological evaluation of betulinic acid derivatives as potent anti-HIV-1 agents

Towards de novo synthesis of structure-defined oligosaccharides with heparan sulfate biosynthetic enzymes	Antimicrobial and wound healing properties of nitric oxide-releasing xerogels and silica nanoparticles

Utility of two distinct macromolecular carriers for nucleic acid delivery	Bioanalytical methods for investigating bacterial adhesion and the antibacterial action of nitric oxide

Role of hepatic transport proteins in drug disposition and drug-induced liver injury	Design, synthesis, and biological evaluation of novel neo-tanshinlactone analogues as potent and selective anti-breast cancer agents

Antibody carriers of CpG oligodeoxynucleotides for solid tumor immunotherapy	Classifier design to improve pattern classification and knowledge discovery for imbalanced datasets

Methods in literature-based drug discovery	A chemical biology approach to discover the biological targets of the antiepileptic drug lacosamide

Design, synthesis, and biological studies of new phenanthroindolizidine and phenanthroquinolizidine analogs as anticancer agents	Development and application of cheminformatics approaches to facilitate drug discovery and environmental toxicity assessment

Alleviating Cancer Drug Toxicity Through Targeted Inhibition of a Bacterial Enzyme and Exploring the Structural and Functional Properties of the Xenobiotic Nuclear Receptor PXR