ProQuest Subject Index - Molecular biology at THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

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You are viewing titles for THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL in the Molecular biology available through the UMI Dissertations & Thesis Gradwoorks site

Detecting DNA damage: The synthesis of new aldehyde reactive probes for the quantitation of apurinic/apyrimidinic sites	Purification and characteriztion of the Danaus plexippus cryptochromes

Assessment of lipopolysaccharide, isoproterenol and phenylephrine induced pathophysiology in lipoic acid synthase deficient mice	Characterizing the pregnane X receptor's interactions and biophysical properties

The role of RasGRP3 in the embryonic response to phorbol esters and diabetes	Overlapping functions of MUS81 endonuclease and DmBlm helicase in DNA repair in Drosophila melanogaster

A comparative study on the effect of integrin subunits beta one and beta three on osteoblast implant interactions	Combined gene therapy of siRNA and apoptosis inducing factor generated from a single transcriptional event

Molecular characterization of beta2 adrenergic receptor haplotypes	Vascular endothelial cadherin phosphorylation modulates endothelial cell permeability and leukocyte transendothelial migration

An O-hydroxylamine-coupled alkaline gel electrophoresis assay demonstrates an accumulation of real single strand breaks and intact AP sites in base excision repair deficient cells	Diagnosis: The buck starts here---The role of diagnosis in three areas of modern medicine

The aging process deconstructed: Glucose production, cancer resistance and longevity	The Pseudomonas aeruginosa Type IV pilus-associated protein PilY1 is required for stable fiber formation and host attachment

The role of MARCKS in mast cell regulated exocytosis	The role of SRY-box (Sox) transcription factors in epithelial stem cell biology of the gastrointestinal tract

Analyzing the diversity of a small antibody mimic library	The Epigenetic Effects of Prenatal Folate Supplementation on Male CD1 Mouse Fetuses Exposed in utero to Arsenic

Regulation of epithelial morphogenesis by Drosophila Rho GTPase and Abl kinase	G protein-coupled receptors in the neuropathophysiology of asthma

Elucidating the roles of the cardiogenic factors Tbx20, Tbx5 and Hsp27 in vertebrate heart development	Structural and mutational analysis of heparan sulfate biosynthetic enzymes

The preparation and characterization of a heparin-derived oligosaccharide that binds to herpes simplex virus type 1 glycoprotein D	Development and characterization of mouse models of human glioblastoma

Analysis of the VEGFR1 (FLT-1) isoforms in vascular development	An in vitro explant model of overuse tendinopathy. The effects of cyclic loading and inflammatory mediators on mechanical and compositional properties of tendons

Investigating septin-dependent, actomyosin-ring-independent cytokinesis in Saccharomyces cerevisiae	Regulation of the G1-S transition by cyclin-dependent kinase inhibitors

Cryptochrome, circadian cycle, cell cycle checkpoints, and cancer	Cell cycle and cell growth regulation by the CUL4-DDB1-ROC1 ubiquitin ligases

Histone mRNA translation in metazoans: SLIP1 as the bridging factor between the 5' and 3' UTRs of the histone mRNA	The genetic architecture of the DDK syndrome: An early embryonic lethal phenotype in the mouse

Histone H3 Lysine 36 modification distinguishes transcribed and non-transcribed regions of the S. cerevisiae genome	A molecular and genetic characterization of the mechanisms of histone mRNA metabolism in Drosophila

Isolation and characterization of genes involved in DNA damage response and telomere maintenance in Caenorhabditis elegans	Role of the yeast histone methyltransferase Set2 and its regulatory domains in RNA polymerase II transcription

Epigenetic defects in stem cells deficient in polycomb group function	Effectors of Haemophilus ducreyi pathogenesis

Investigating the role of ankyrin repeat and SOCS box protein 4 (ASB4) during vascular development	Function and activation of signal transducer and activator of transcription 3 (STAT3) in adipose tissue formation and metabolism

Mechanisms of estrogen sensitivity in the human endometrium	Conservation and function of the histone methyltransferase Set2

Functional characterization of DJ-1: An oxidative response protein	Investigating the role of IKKepsilon (epsilon) in cancer-associated NF-kappaB activity

Molecular identity and nutrient limitation of Lyngbya wollei mat communities in north Florida freshwater systems	Roles of auxin response factors in Arabidopsis flower development

Determining the role of prostanoids in the pathogenesis of pulmonary fibrosis	Regulation of cell survival by CIB1, a new modulator of 3-phosphoinositide-dependent protein kinase 1 (PDK1)

MutL involvement in two DNA repair pathways: Methyl-directed mismatch repair and very short patch repair	Physiologic effects of cytochrome P450 3A activity

Arabidopsis response regulators in cytokinin signaling and development	Structure and function of Tetrahymena thermophila telomerase RNA

Regulation of tight junction barrier function by phospholipase C	Breast cancer subtypes, mouse models, and microarrays

IRS-1 and SOCS2 are key regulators of insulin-like growth factor signaling in intestinal cancer	Molecular mechanisms of TBX20 regulation

Pathway of histone mRNA degradation: Oligouridylation followed by bidirectional decay	Molecular mechanisms specifying the topography of thalamocortical projections in the ventral telencephalon

The transforming Rho family GTPase, Wrch-1, regulates epithelial cell morphogenesis through modulating cell junctions and actin cytoskeletal dynamics	Inclusion of a glycogen regulation mathematical model into a contextual metabolic framework

Effect of pyrethroid insecticides on gene expression in the mammalian central nervous system	Impact of diet on EGFR-targeted treatment of colorectal cancer

A functional analysis of the role of SHP-2 in vertebrate heart development	Defining diverse mechanisms that regulate the activity of Dbl-family guanine nucleotide exchange factors

Genesis of end-to-end chromosome fusions	The involvement of Wnt signaling in osteoblastic cell behavior

Diversity within the master regulatory p53 transcriptional network: Impact of sequence, binding motifs and mutations	Androgen receptor and epidermal growth factor signaling in prostate cancer

The role of protein degradation in maintaining genome stability through regulation of origin licensing	Structural and mechanistic studies of mammalian mitochondrial RNAs

The regulation of myocardin factor dependent transcription in vascular smooth muscle	Genetic and molecular characterization of Roc-Cullin interactions in Drosophila melanogaster E3 ubiquitin ligases

DNA damage response to lesions involving both strands of the double-helix	Density-enhanced protein tyrosine phosphatase 1 (DEP-1) regulation of epithelial cell adhesions

Two leucine-rich receptor kinases mediate signaling linking cell wall biosynthesis and ACC synthase in Arabidopsis and possible downstream elements in the pathway	Biochemical characterization of human heparan sulfate 6-O-endosulfatase

Regulation and function of the cerebral cavernous malformation 2 protein	Examining the role of the U7 snRNA in histone pre-mRNA processing and the U7 snRNP dependent and independent roles of Lsm10 and Lsm11, two novel Lsm proteins in Drosophila

Expression of the Gi-coupled RASSL Ro1 in GFAP-positive cells: A novel model of hydrocephalus	The regulation of constitutive NF-kappaB by glycogen synthase kinase-3 in pancreatic cancer

Functional analysis of CASTOR in vertebrate cardiomyocyte differentiation	Structural analysis of protein-facilitated cooperative folding in the bI3 RNP

The function of a novel guidance molecule, Plexin-A1, on immune dendritic cells	Characterization of Ras-driven melanoma: Understanding the relationship between acute loss of p16INK4a and somatic activation of Ras in melanomagenesis

The genomic distribution and function of NFI and histone variant H2A.Z during C. elegans development	Molecular characterization of a replication licensing checkpoint

Genetic mouse models elucidate the roles of adrenomedullin in cardiovascular development and physiology	Ras family GTPases involved in breast cancer

Epigenetic regulation of gene transcription: Jhdm1b characterization and genome-wide localization of H2A ubiquitylation	Embryonic regulation and post-embryonic function of the single-minded gene in the Drosophila central nervous system

Cotranscriptional processing of histone pre-mRNA	Simulation methods for spatiotemporal models of biochemical signaling networks

Understanding crossover control using A. thaliana and S. cerevisiae	Toward a recombinant adeno-associated virus origin of replication

Development and use of genetic reporters to identify Mycobacterium tuberculosis exported proteins important for virulence	Investigation of probe substrates to assess hepatic transport function

Factors affecting the formation, stability, and expression of unintegrated lentiviral vector genomes	Nanoparticle delivery of siRNA for cancer therapy

The role of the NF-kappaB pathway in Her2-overexpressing breast cancer	Tyrosine kinase modulation of trafficking and biological functions of the atypical Rho GTPase, Wrch-1

G protein signaling at the endosome	Characterization of a tryptophanyl-tRNA synthetase urzyme and its intramolecular complementation establishes a model to study the catalytic mechanism and evolution of the contemporary class I aminoacyl-tRNA synthetases

The use of reporters to identify factors involved in 3' end processing of nonpolyadenylated RNA polymerase II transcripts	Genetic and pharmacologic regulation of cyclin dependent kinase 4 and 6 activity in mammalian hematopoiesis

Identification of a nuclear export signal in the catalytic subunit of AMP-activated protein kinase	The effects of DJ-1 and A20 family members on inflammation and oxidative response

Development and validation of an assay for the characterization of the DNA damage response to damage caused by Superfund chemicals	Glucocorticoid regulation of microRNA expression modulates lymphocyte apoptosis

An NMR-compatible bioartificial liver for metabolomic investigation of drug action	Telomerase and cellular aging: Analysis of telomerase RNA structure and the impact of telomerase on miRNA expression

Molecular stratification and characterization of clear cell renal cell carcinoma	Stromal promotion of metastasis by erythroid differentiation regulator 1

Sphingosine-1-phosphate and the RGS RhoGEFs regulate vascular smooth muscle phenotype	The regulation of let-7 microrna biogenesis in early embryogenesis

Prouroguanylin's role in the homeostatic response to dietary sodium: Hormone precursor or active signaling agent?	Serine Proteases and Serine Protease Inhibitors in Breast Cancer Cell Pathophysiology

Stable-isotope probing-based investigations of polycyclic aromatic hydrocarbon-degrading bacteria in contaminated soil	The Ras activator RasGRP3 mediates diabetes-induced embryopathy and ET1-induced vessel morphogenesis

Understanding the mechanism of mTOR inhibition in Human Herpes Virus-8 associated malignancies	Biglycan Modulation of Bone Morphogenetic Protein-2 Functions

Detection and Analysis of Common Fragile Sites in Drosophila melanogaster	PIE - The Protein Inference Engine

The Role of Myosin-X in a Putative System of Intrafilopodial Transport	On the role of the phosphatidylinositol transfer protein alpha in the nuclear import of phosphatidylinositol

Examining novel roles for the IkappaB kinase in coordinating the cellular response to metabolic stress	Innate immune responses to the commensal microbiota in zebrafish

Exploring Protein Backbone Designability: The Computational Redesign and de novo Design of Helix Bundle Proteins	Identifying Molecular Mechanisms of Catechol O-Methyltransferase Activity and Regulation

Composition, structure, dynamics and function of c-type lectin receptor domains	Implications of the shape of telomerase RNA

S phase-coupled E2f1 destruction ensures homeostasis in proliferating tissues	Develop Small Molecule Regulators of GTPase-activating Proteins of ADPribosylation Factors (ARFGAPs)

The role of Set2, transcription factor residence, and nucleosome spacing in the dynamic access of genomic information	The FhaB Prodomain of Bordetella Affects the Biogenesis of Filamentous Hemaggluttinin, Influencing Bordetella Virulence

DiGeorge syndrome phenotypes reflect disrupted interaction between inductive signals and 22q11 genes