ProQuest Subject Index - Genetics at THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

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You are viewing titles for THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL in the Genetics available through the UMI Dissertations & Thesis Gradwoorks site

Effect of minor SNPs on enzymatic activity regulated by common human haplotypes of the catechol-O-methyltransferase gene	Assessment of lipopolysaccharide, isoproterenol and phenylephrine induced pathophysiology in lipoic acid synthase deficient mice

Genome-level analysis of genetic regulation of liver gene expression networks	Overlapping functions of MUS81 endonuclease and DmBlm helicase in DNA repair in Drosophila melanogaster

Diagnosis: The buck starts here---The role of diagnosis in three areas of modern medicine	The role of SRY-box (Sox) transcription factors in epithelial stem cell biology of the gastrointestinal tract

Phenotype Characterization And Candidate Genotyping Of Hypodontia In Ectodermal Dysplasia (ED) And Non-Syndromic Groups	Repair of base-base mismatches and four-base loops formed during meiotic recombination in S. cerevisiae

G protein-coupled receptors in the neuropathophysiology of asthma	Development of biologically based therapies for basal-like breast tumors

Heteroduplex DNA and meiotic recombination in Drosophila	Development and characterization of mouse models of human glioblastoma

Evolution of a snake mimicry complex	Regulation of the G1-S transition by cyclin-dependent kinase inhibitors

Regulation of the stability of plant disease resistance proteins	The genetic architecture of the DDK syndrome: An early embryonic lethal phenotype in the mouse

A molecular and genetic characterization of the mechanisms of histone mRNA metabolism in Drosophila	Novel roles for adenomatous polyposis coli family members and wingless signaling in cell adhesion and axon outgrowth during Drosophila brain development

Selection and analysis of mitotic crossovers in Saccharomyces cerevisiae	Isolation and characterization of genes involved in DNA damage response and telomere maintenance in Caenorhabditis elegans

Epigenetic defects in stem cells deficient in polycomb group function	DNA damage response in Drosophila melanogaster: Orchestrating repair with cell cycle checkpoints

Thermal adaptation of the phage G4 and molecular evolution of RNA secondary structure	Statistical aspects of haplotype-based association studies

Characterization of the tumor suppressor capabilities of SWI/SNF complex member BAF155 in cancer cell lines and cooperation of SNF5 and p53 pathways	Regulation of E2f1-target gene expression during Drosophila embryogenesis

Determining the role of prostanoids in the pathogenesis of pulmonary fibrosis	Physiologic effects of cytochrome P450 3A activity

Evolution of the host range of the bacteriophage &phis;6	Genetic investigation of both complex and Mendelian disorders: Neural tube defects and Native American myopathy

Breast cancer subtypes, mouse models, and microarrays	The importance of ERBB receptor tyrosine kinase signaling in colorectal cancer---Implications for EGFR-targeted therapies

Molecular mechanisms of TBX20 regulation	Functional analysis of EGFR using a conditional allele

Histological and molecular analysis of colorectal cancer morphology	Microbial pathogen-induced necrosis mediated by NLRP3 and ASC

Impact of diet on EGFR-targeted treatment of colorectal cancer	Use of an allelic series in mouse to study the role of epidermal growth factor receptor in placental development and pregnancy

Genesis of end-to-end chromosome fusions	Influence of diet and maternal dioxin on endocrine disruption: Puberty, metabolic syndrome, and breast cancer

Genetic mouse models reveal key physiological functions of adrenomedullin signaling	Characterization of a murine hypomorphic allele of the spindle checkpoint gene Bub1 and its role in tumorigenesis

Diversity within the master regulatory p53 transcriptional network: Impact of sequence, binding motifs and mutations	Regulation of ethylene biosynthesis via ACC synthase protein stability

Development and characterization of mouse models of human breast cancer	Genetic and molecular characterization of Roc-Cullin interactions in Drosophila melanogaster E3 ubiquitin ligases

DNA damage response to lesions involving both strands of the double-helix	Examining the role of the U7 snRNA in histone pre-mRNA processing and the U7 snRNP dependent and independent roles of Lsm10 and Lsm11, two novel Lsm proteins in Drosophila

The regulation of constitutive NF-kappaB by glycogen synthase kinase-3 in pancreatic cancer	Characterization of cellular and viral microRNAs in Kaposi's sarcoma-associated herpesvirus malignancies

Characterization of Ras-driven melanoma: Understanding the relationship between acute loss of p16INK4a and somatic activation of Ras in melanomagenesis	The genomic distribution and function of NFI and histone variant H2A.Z during C. elegans development

Genetic mouse models elucidate the roles of adrenomedullin in cardiovascular development and physiology	Embryonic regulation and post-embryonic function of the single-minded gene in the Drosophila central nervous system

Human genetic susceptibility to mother to child transmission of HIV: A study of mother-infant pairs in Malawi	Understanding crossover control using A. thaliana and S. cerevisiae

Identification and characterization of neural progenitor cells in the central nervous system using the transcription factor SOX2	Development and use of genetic reporters to identify Mycobacterium tuberculosis exported proteins important for virulence

The genetics of obesity-related traits and lipoproteins in Filipino women	Ras signaling through the RalGEF-Ral pathway in C. elegans

Factors affecting the formation, stability, and expression of unintegrated lentiviral vector genomes	A murine model of genetic determinants of RSV disease

Regulation of cell separation during organ abscission in Arabidopsis thaliana	The role of the NF-kappaB pathway in Her2-overexpressing breast cancer

Genome-wide analysis of transcriptional regulation in the murine liver	An alphavirus NSP1 determinant modulates type I interferon induction

Identification of a nuclear export signal in the catalytic subunit of AMP-activated protein kinase	Regulation of adventitia-resident progenitor cells

Telomerase and cellular aging: Analysis of telomerase RNA structure and the impact of telomerase on miRNA expression	Molecular stratification and characterization of clear cell renal cell carcinoma

Single nucleotide polymorphisms (SNPs) in occupational exposure assessment	Clinical implementation of breast cancer genomics

Peroxisome proliferator activated receptor-gamma P465L mutation in diabetes and atherosclerosis	High level integration of genomic data for improving prediction, prognostication and classification of breast tumors

Metabolic substrates exhibit differential effects on functional parameters of mouse sperm capacitation	Dissecting the genetic architecture of complex traits: Hot spots and vascular collaterals

Linkage, Association, And Haplotype Analysis: A Spectrum Of Approaches To Elucidate The Genetic Influences Of Complex Human Traits	Detection and Analysis of Common Fragile Sites in Drosophila melanogaster

Uncovering the protective role of PolgD257A, a mitochondrial DNA mutator, on diabetes and obesity	Determining the role of the Xist non-coding RNA in Epigenetic Programming of X-chromosome Inactivation

Pre-clinical assessment of genetic and neurobiochemical markers for depressive behavior and antidepressant response	Examining novel roles for the IkappaB kinase in coordinating the cellular response to metabolic stress

Exploring the genetic basis of chronic periodontitis: A genome-wide approach	Regulation and function of Drosophila single-minded in the postembryonic brain

Joint effects of alcohol consumption and polymorphisms in alcohol and oxidative stress metabolism genes on risk and survival from head and neck cancer	Genetic analysis of Vprbp in mice

Innate immune responses to the commensal microbiota in zebrafish	Model-based approaches to multiple hypothesis testing for RNA-seq and other genomic platforms

Genetic analysis of innate immune receptor accumulation and function in plants	S phase-coupled E2f1 destruction ensures homeostasis in proliferating tissues

Genetic Regulation of Cell Death and Disease Resistance in Arabidopsis	The role of Set2, transcription factor residence, and nucleosome spacing in the dynamic access of genomic information

DiGeorge syndrome phenotypes reflect disrupted interaction between inductive signals and 22q11 genes	A systems level analysis of transcriptional regulation in the yeast mating response