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You are viewing titles for THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL in the Biophysics available through the UMI Dissertations & Thesis Gradwoorks site
 
Characterizing the pregnane X receptor's interactions and biophysical properties
Structural and mutational analysis of heparan sulfate biosynthetic enzymes
 
Development of a magnetic manipulator for microbiological and single molecule investigations
The morphology and biomechanics of the muscle articulation: A new class of soft tissue joint
 
Structural insights into xenobiotic and organophosphate binding by human carboxylesterase 1 and efforts made towards the characterization of the androgen receptor modulator MAGE-11
Probing protein structural dynamics using simplified models
 
Determining and modulating E2-HECT binding affinity and specificity
Agnostic Tracking: Nanoscale, high bandwidth, 3D particle tracking for biology
 
Analytical studies on the mechanism of fibrin formation
Bacterial conjugation and its inhibition: The hows and whys of conjugation and what can be done to control it
 
The role of pH, self-association, and lipid binding in vinculin tail structure and function
Protein behavior in crowded environments
 
Dynamic regulation and information transfer in intra-cellular signaling pathways
The dock family of atypical guanine nucleotide exchange factors: Regulation by ELMO1 and RhoG
 
Design, fabrication, and actuation of biomimetic cilia
Computational redesign of protein-protein interactions
 
Overcoming obstacles to nonhomologous end joining repair of chromosome double strand breaks
Computational modeling and automation techniques to study biomolecular dynamics
 
Molecular dynamics computer simulations of lipid bilayers containing cholesterol
Multi-scale modeling of the structure and dynamics of macromolecules
 
Filamin: A family of mechanosensory scaffold proteins
The mechanism of Cu,Zn superoxide dismutase oligomerization in familial amyotrophic lateral sclerosis
 
Representation and selection of time-varying signals by single cortical neurons
Using noncanonical amino acids in computational protein design
 
Computational design of novel proteins for affinity reagents
Atomistic simulations uncover microscopic details of nucleosomal electrostatics, energy landscapes of proteins and photovoltaic polymer dynamics.
 
Small particle transport in fibrin gels and high throughput clot characterization
Structural and Functional Studies of E. coli Conjugative Relaxase-Helicase TraI and Arabidopsis thaliana Protein Arginine Methyltransferase 10 (PRMT10)
 
Protein NMR in Insect and Bacterial Cells
Modeling Cell-Extracellular Matrix Interactions: Spatial and Conformational Control of Ligand Presentation on Self-Assembled Monolayers
 
Recognition of platinum-DNA adducts by HMG-box proteins
The Role of Myosin-X in a Putative System of Intrafilopodial Transport
 
Drosophila melanogaster myosin-18 represents a highly divergent molecular motor with actin tethering properties
Investigation of Phosphorylation and Ligand Binding of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase
 
Exploring Protein Backbone Designability: The Computational Redesign and de novo Design of Helix Bundle Proteins
Identifying Molecular Mechanisms of Catechol O-Methyltransferase Activity and Regulation
 
Composition, structure, dynamics and function of c-type lectin receptor domains
Sensing the light: Design of photoactivatable protein-protein interactions using the LOV2 domain
 
Structural dynamics of retroviral genomes
Structure and function of the NES relaxase and C-terminal domains required for vancomycin resistance transfer
 
Spatiotemporal dynamics of gradient sensing and polarization in yeast
Macromolecular Crowding and Protein Chemistry: Views from Inside and Outside Cells
 
Advanced Computer Simulations Of Nanomaterials And Stochastic Biological Processes
Total Internal Reflection -- Fluorescence Correlation Spectroscopy (TIR-FCS): Application to the Study of Ligand -- Receptor Interactions
 
Design of protein-protein interactions via beta-strand pairing
Structural and therapeutic insights from the HIV-1 RNA genome
 
A systems level analysis of transcriptional regulation in the yeast mating response