ProQuest Subject Index - Cellular biology at THE JOHNS HOPKINS UNIVERSITY

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You are viewing titles for THE JOHNS HOPKINS UNIVERSITY in the Cellular biology available through the UMI Dissertations & Thesis Gradwoorks site

Hypoxia induced Epstein-Barr virus lytic infection. What can be learned from a drug screen?	The surface organization of MHC class I molecules regulates their recognition by T-cells

A microfabrication approach to study cell-cell interactions in proliferative regulation	Immediate early genes and synaptic transmission: Protein synthesis-dependent synaptic plasticity and homeostatic adaptation

Transcriptional control of glucose homeostasis through SIRT1 and PGC-1alpha	Tsunami is required for directional responses of Dictyostelium in chemotactic gradients during development

The role of Kruppel-like factor four in hematopoiesis	Control and information-theoretic analysis of biological signaling systems

The repopulation and regulation of two different stem cell lineages in one stem cell niche: The germline and somatic stem cells in the Drosophila testis	Genetic and mechanical analysis of tube morphogenesis in the living Drosophila embryo

The calcium signaling pathway, endoplasmic reticulum stress, and programmed cell death in the yeast Saccharomyces cerevisiae	A novel mechanosensory feedback system controls cell shape progression during cytokinesis

The role of the polyamine catabolic enzymes spermine oxidase (SMO) and spermidine/spermine N1-acetyltransferase (SSAT) in the drug response of human non-small cell lung cancer cells	Novel therapeutic agents for prostate cancer treatment: Design of bulky anti-androgens, thapsigargin analogs and inhibitors for prostate specific antigen

An evolutionarily conserved role for the C. elegans Bcl-2 homolog CED-9 at mitochondrial membranes	Characterization of double-strand break-induced cohesin domain assembly and function

The MMM2 protein controls mitochondrial shape in Saccharomyces cerevisiae by determining mitochondrial protein content	Identification of transcription factors that direct dopaminergic neuron development through the regulation of NURR1 expression

Investigating the differentiation of mesenchymal stem cells in two-dimensional and three-dimensional multicellular environments	Light, Lymphotoxin beta receptor and herpes virus entry mediator: Mediators of cell death and proliferation

Modeling HIV as a Trojan Exosome	Analysis of Drosophila melanogaster germline sex determination

Cullin 5 E3 ubiquitin ligase: Viral and cellular functions	Intracellular organization of tapasin is essential for efficient assembly of MHC class I molecules within the endoplasmic reticulum and their subsequent cell surface expression

Oxygen sensing and regulation of sterol homeostasis in fission yeast and mammals	Oxygen sensing and hypoxic gene regulation in fission yeast

Functional and molecular characterization of a primitive bone marrow-derived stem cell	New player in an old field: Tiarin, a novel actin binding protein, to regulate actin cytoskeleton and cell migration in Drosophila ovary

A functional genomic characterization of the Drosophila fusome	In vivo characterization of endocytic adaptors as regulators of clathrin-mediated endocytosis

Genetic regulation of collective cell migration	Cytokinesis contraction through the remodeling of a disordered actin network

Antiviral APOBEC3 genes: Expression, regulation and association with clinical markers	Novel viral and cellular functions of the E3 ubiquitin ligases: Cullin 4 and Cullin 5

MCF7 side population cells and sphere culture as models for breast cancer stem-like cell biology and drug identification	The association of polycystin-1 with apical-basolateral and planar cell polarity complex and its biological implications

The importance of animal models in understanding cell death: Lessons from genetically engineered mice	Dissecting cell fate decisions in human embryonic stem cells

Crossing the divide: Molecular determinants of Toxoplasma invasion and egress	Global assessment of melanoma-endothelial cell communication identifies neuropilin-2 as a mediator of melanoma cell proliferation

Functional studies of rare CFTR missense mutations facilitate interpretation of genotype-phenotype relationships	Functional dissection of the essential nucleosome acetyltransferase of H4 (NuA4) complex with genomics and proteomics approaches

Investigating rate-limiting barriers to nanoscale nonviral gene transfer with nanobiophotonics	Cellular engineering strategies for improvement of mammalian cell phenotypes in commercial applications

Characterization of EF-G-dependent translocation in Bacillus stearothermophilus	The copper chaperone as a dual regulator of effects related to oxidative stress and chromatin remodeling

Characterization of the trans and cis presentation functions of IL-15 receptor alpha on tumor cells and T cells	CK2 and Sumo1 phosphorylation: A role in cell survival

Multiple calcium signaling pathways regulate yeast cell death during the response to mating pheromones	Analysis of the molecular mechanisms regulating paralogue-specific SUMOylation and its effects on protein function

Inhibition of the cholesterol biosynthetic pathway modulates the innate immune response	Novel proteins and novel functions: Probing the unusual mitochondrial biology of trypanosomes

Anti-inflammatory mechanisms of minocycline: Suppression of T cell proliferation, activation and cell cycle progression	Regulation of MBK-2/DYRK during the oocyte-to-embryo transition

Fibrin(ogen) is a CD44 ligand on colon carcinoma cells: Biochemical and biophysical characterization, growth factor involvement, and diagnostic applications	Illuminating spatiotemporal regulation of cyclic AMP signaling dynamics in live cells using novel FRET-based biosensors

Metamorphosis of Plasmodium sporozoites into exoerythrocytic forms: Discovery of novel degradative pathways in the malaria parasite	In-vitro T cell death induced by Aldrithiol-inactivated HIV virions as a model for T cell homeostasis failure in people with HIV-1 infection

Molecular regulation of neural stem cells and activity-dependent neurogenesis in the adult brain	Protein quality control in the endoplasmic reticulum and cytosol

Mitochondrial regulation of Leydig cell steroid synthesis. Implications for the decline in male testosterone production with advancing age	Physical and functional interaction between Sindbis virus and neurons: nsP3 macro domain, PARP-1 and NF-kappa B

Signaling roles for emerin at the nuclear inner membrane	Retinoic acid signaling in the development of spinal motor neurons

Comparative studies of efferent cholinergic inhibition in cochlear inner and outer hair cell	Study of the molecular mechanisms by which alpha4 beta1integrin promotes cell migration

Cellular and molecular mechanisms of gap junction traffic in the heart	Formation and maintenance of epithelial tubes: From mechanics to cell death

Regulation of sexual dimorphism in the Drosophila melanogaster gonad	Neural stem cell proliferation and differentiation on functional electrospun fiber matrices

mTOR controls mitochondrial function through the YY1 transcriptional complex	Exploration of enveloped virus biogenesis and anti-viral resistance

Self-organization of keratin intermediate filaments into crosslinked networks	Protein-protein interactions at the Golgi complex and their roles in apoptosis and mitosis

Engineering the extracellular matrix environment to investigate dynamic cellular responses	Regulation of vascular inflammation by aldosterone and histone deacetylases

Cellular responses to spatial information in the microenvironment	Degradation of cAMP and regulation of adenylyl cyclase activity controls group migration and signal relay in the social amoebae Dictyostelium discoideum

Programmed subcellular release to study the dynamics of cell detachment	Genetic analyses of cell migration in vivo

Regulation of the Hif-1 transcription factor by interacting proteins	The interferon beta response to simian immunodeficiency virus infection of the central nervous system: Induction, regulation, and effects

Sister chromatid cohesion generation: From regulation to mechanism	Insights into mammalian sperm-egg adhesion and fusion from studies of knockout mouse models of male infertility

Dictyostelium discoideum possess a highly diverged presenilin/gamma-secretase that accurately processes human amyloid precursor protein and is required for growth and correct cell fate determination	SARS coronavirus spike protein trafficking

Regulation of the simian immunodeficiency virus long terminal repeat by C/EBP beta and IFN beta-mediated innate immune responses in vitro and in vivo	Cellular targets of the adenovirus E4 oncoproteins

The role of Tristetraprolin (TTP) in hematopoiesis and homeostasis	UCH-L1 and cystic fibrosis: A novel role for the deubiquitinating enzyme in CFTR biogenesis

Development and characterization of a novel suspension cell line and its application for cell-based influenza virus propagation	Targeting malignant B cell self-renewal and differentiation

Epigenetic and hormonal regulation of stem cell maintenance in the Drosophila testis niche	The structural role of dynamitin in dynactin

Transmembrane helix dimerization in lipid bilayers and mammalian membranes	The genetics of desiccation tolerance in Saccharomyces cerevisiae

Identification of a Golgi targeting signal in the cytoplasmic tail of the severe acute respiratory syndrome coronavirus envelope protein	The dynamic regulation of mitochondrial morphology and mitofusin function by Bax

Dynamic regulation of stereocilia length by unconventional myosins and their actin-regulatory cargo	Characterization of the ezrin-Chloride Intracellular Channel 4 interaction

LAH4: A novel cell-penetrating peptide for application in tumor immunotherapy	Microfluidic assays for studying cell signaling from a systems biology approach

The mechanics of cell-cell and cell-stroma interactions during cancer progression	Regulation of intracellular calcium signaling by polycystin 1 expression

Germline stem cell establishment, loss, and regeneration in the Drosophila testis	Function and regulation of calcium and manganese homeostasis and signaling by secretory pathway calcium-ATPases

Subcellular organelles in neurodegeneration and neurobiology	Nutrient and hormonal control of the protein deacetylase SIRT1

Understanding the role of androgen receptor signaling in breast cancer	The migration and invasion of prostate fibroblasts: A potential contributor to prostate cancer metastasis

Characterizing cytoskeleton-mediated biophysical defects in laminopathic disease models	Variations on a theme: Transcriptional regulation mediated through post-translational modification and microRNA function

B-cell trafficking and long-term maintenance in the CNS of Sindbis virus infected C57BL/6 mice	Leydig cell stem/precursor cells in neonatal, adult and aged testes

Maintenance of nuclear morphology in the yeast, Saccharomyces cerevisiae	The role of FIS1 in the recruitment of mitochondrial fission factors and its interaction with membranes

Understanding directed cell migration: From image processing to mathematical modeling	O-GlcNAc as a regulator of cell death, cell proliferation, and metabolism

A comprehensive study of the autonomy of hedgehog signaling in B cell lymphopoiesis and immune function	Regulation of cell migration by cytoplasmic interactions of alpha 4 integrin

Regulation of cell function by mechanical signaling: Implications for tissue repair and cardiac regenerative medicine	Regulation of CARD11 activity by the kinesin GAKIN and lymphoma-associated mutations

Self-folding devices for biomedical applications	Visualizing signal transduction: Revealing the molecular mechanisms of cAMP signaling specificity

Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex	A protein microarray based approach to discovering novel signaling pathways contributing to cancer and viral pathogenesis

Symmetry breaking and polarization of the C. elegans zygote by the polarity protein PAR-2	Applying proteomics to interpret physiological processes in Chinese hamster ovary cells, Danio rerio and Drosophila melanogaster

The role of nucleo-cytoskeletal connections in disease and development	Computational models of cell division

Lamin B3 antagonizes the mitotic kinesin EG5 to restrain microtubule movements during spindle assembly	The translocation of unusually small proteins

Engineering vascular networks using synthetic matrices	Cancer cell motility in three dimensions: The role of focal adhesion proteins, matrix metalloproteinases, and the extracellular matrix

Oxygen-dependent regulation of SREBP in fission yeast	The coronavirus envelope protein has multiple roles in virus assembly and trafficking

Vesicular sorting of AMPA, GABAA, and NMDA receptors during exocytosis	Live-cell imaging studies of collective cell migration and tissue elongation using Drosophila egg chamber

Investigations of TRPV2 in murine peritoneal macrophages	The role of mutant KRAS and PIK3CA in human breast cancer tumorigenesis

Histone acetyltransferase p300/CBP as a functionally significant target in melanoma	A novel method for analyzing the human CD8+ T cell repertoire reveals age based changes in responses to influenza epitopes

Oscillatory signaling cascades govern phenotypic outcomes in proximal tubular epithelial cells	Influenza A virus interactions with host cells: From cell tropism to nuclear targeting

Redox biology and the aging Leydig cell	The multi-faceted role of selectin ligands in tumor cell metastasis

Regulation of skin keratin intermediate filament proteins by phosphorylation	Cell morphology changes induce the expression of growth differentiation factor 15 (GDF15), a marker of metastasis

Blown fuse, a novel regulator of podosome dynamics and invasion during myoblast fusion