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Inhibition of ErbB-2 activates Notch-1 through cell surface accumulation of Notch-1 and its ligand, JAG-1 and sensitizes ErbB-2 positive breast cancer cells to a GSI
Protein kinase C delta is critical for nucleotide excision repair of cyclobutane pyrimidine dimers
 
Determination of the molecular mechanisms of hyperglycemia-induced changes in CaV3.2 calcium channel properties
Synthesis and characterization of a novel hemoglobin based blood substitute
 
Theoretical studies on protein conformational changes and the associated ligand binding and diffusion pathways
Biophysical studies on the pharmacological action of lithium
 
Fluorescence and NMR studies on the competition between Li+ and Mg2+ for native and mutated Gialpha1 proteins
Role of phosphorylation events in neuroprotection due to ethanol preconditioning
 
Enzyme-catalyzed phosphoryl transfer reactions: Energetics of transition states and vanadate analogues in aqueous solution
Design, synthesis and biological evaluation of folate-targeted photodynamic therapy agents
 
Protein tyrosine phosphatase 1B: A target for vanadium's insulin-enhancing behavior
Functional evolution and origin of enzymes of the bacterial glycogen/starch biosynthetic pathway
 
The tumor suppressor PKCdelta is critical for UV-induced G2/M checkpoint activation and apoptosis
CaMKII-mediated phosphorylation of the inositol 1,4,5-trisphosphate receptor at serine-150 results in decreased channel activity
 
Involvement of the NMDA receptor in moderate ethanol preconditioning-dependent neuroprotection from amyloid-beta in vitro
Role of non-coding RNA NC4 in MLL and CYP33 mediated regulation of HOXC8
 
The role of CYP33 in MLL mediated gene repression