ProQuest Subject Index - Molecular biology at HARVARD UNIVERSITY

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You are viewing titles for HARVARD UNIVERSITY in the Molecular biology available through the UMI Dissertations & Thesis Gradwoorks site

Trafficking of synaptic proteins and tomosyn inhibits synaptic vesicle priming	Mechanisms and consequences of crosstalk among plant defense pathways encoding resistance to pathogens and herbivores

Regulatory pathways governing biofilm formation in Bacillus subtilis	Life before the rise of oxygen: Insights from a Late Archean carbonate platform in South Africa

The microbial ecology of a polluted, stratified lake: Methanotrophy, biodegradation, sulfate reduction, and methanogenesis	Mutation rate variation in the yeast, Saccharomyces cerevisiae

Antigen-specific T cell responses to Chlamydia trachomatis	Characterization of microRNAs mediating olfactory neurogenesis

The evolution of multicellularity and phenotypic mutation rates	The M2 splice isoform of pyruvate kinase is a phosphotyrosine binding protein critical for tumor cell metabolism and proliferation

Characterization of a novel E3 ubiquitin ligase in Fanconi anemia	Regulation of amyloid-beta protein levels by proteolytic degradation and its implications for Alzheimer's disease

Modulation of promoter escape by sigma-core interactions of the bacterial RNA polymerase holoenzyme	The role of PI3K p110alpha and p110beta isoforms in oncogenesis

Systems analysis of RNA-binding proteins and regulated mRNA processing	Regulation of immunobiology and skeletal biology by the zinc finger adaptor protein Schnurri-3

Characterization of the lprG-Rv1410c operon in Mycobacterium tuberculosis	Dysregulation of the MiT family of transcription factors in melanoma

Cell entry of New World hemorrhagic fever arenaviruses	A study of the mechanism and method to control the degradation of Mad1 by regulating ubiquitin ligase activity of c-IAP1

Activating mutations of N-WASP reveal novel roles for N-WASP during Shigella infection	Negative regulation of RNA interference in Caenorhabditis elegans

Investigation of transcription initiation from cryptic promoter sites in Saccharomyces cerevisiae	The host-parasite interface: Investigations into the factors that mediate entry of human erythrocytes by Plasmodium falciparum

Regulated ATF4 persistence in cell cycle control and neurogenesis	NMR solution structure of the C-terminal domain of the Fas apoptosis inhibitory molecule (FAIM)

Mechanisms coupling steps in gene expression	Subcellular localization and compartmentalization of the ClpP proteases in B. subtilis

A functional characterization of G3BPs	Ribosomal heterogeneity and translational regulation in Saccharomyces cerevisiae

Dynamic regulation of histone lysine methylation	Identification and characterization of histone gene amplification as a method for dosage compensation in Saccharomyces cerevisiae

Investigation of the role of MDMX in p53 regulation	A role of the Fanconi Anemia pathway in error-prone DNA damage tolerance

The regulation of connective tissue growth factor in fibroblasts by a soluble Trypanosoma cruzi factor	The roles of secreted antibody and bir variant antigens in immunity to Plasmodium berghei

The role of nucleosomes in heterochromatin assembly in Saccharomyces cerevisiae	The role of microcephalin in cell cycle regulation and embryonic development

Structural and biochemical studies of bacterial nucleotide excision repair	The molecular logic of pheromone stimulus coding in the mouse vomeronasal system

Function of the Rpb4 subunit of RNA polymerase II during transcription	microRNA regulation of synapse function in C. elegans

The role of MSL3 in Drosophila dosage compensation	Dynamic and temporal aspects of RNA production and processing

Analyses of CCR5 coreceptor usage by the third variable loop of human immunodeficiency virus type 1 subtype D gp120	Quantitative studies of microRNA-mediated regulation

Regulation of self-renewal by leukemogenic mutations associated with acute promyelocytic leukemia	YY1 functions in homologous recombination DNA repair and mice spermatogenesis

Carrier protein tailoring, recognition, and applications for protein labeling	Extracting information from proteomic data through statistical modeling

Genetic analysis of small RNA-mediated gene silencing in C. elegans	Biochemical and structural analysis of the protein machinery required for outer membrane protein biogenesis in Escherichia coli

Cellular responses that preserve genome stability in S. cerevisiae	Regulation and function of the NF1 tumor suppressor

RNA folding: Monte Carlo simulation and single molecule experiments	Kruppel-like factor 2 as a central link between blood flow and vascular endothelial function

Properties of the SID-1 double-stranded RNA channel	Functional analysis of cullin-based ubiquitin ligase and a novel UBC domain-containing protein

Identification of novel functions of the Paf1C and Npl3 during RNA polymerase II transcription elongation	Regulation of gene expression in T lymphocytes by the transcription factor Runx3

HIV/SIV variable loops as targets and elicitors of antibodies that neutralize viral infectivity	Chromosome dynamics in Bacillus subtilis

Modeling primordial germ cell formation in vitro	Probing transcriptional regulation in mammalian cells

Analysis of cerebrospinal fluid in brain development	Fluctuations from single molecules and single cells

Novel roles of NOTCH and JAK3 during normal and malignant hematopoiesis	Functional significance of neuronal activity-dependent transcriptional regulation in the nervous system

The genetics and evolution of the Winters sex-ratio in Drosophila	Elucidating the activation properties of the Th2 PAMP, Lacto-N-fucopentaose III

Nuclear import and synapse to nucleus signalling at the Drosophila neuromuscular junction	Global approach toward the identification of transcription factor substrates of F-box proteins in S. cerevisiae

A systems approach to the evolution of cooperation	Mechanistic studies and practical applications of direct reprogramming

Development of lysate microarray technology for quantitative analysis of EGFR signaling	Complex patterns of speciation and diversity among African frogs (genus Phrynobatrachus)

The SLX4/BTBD12 complex: A molecular toolkit for DNA repair	Chromatin-modifying enzymes of the 2-oxoglutarate and iron(II)-dependent oxygenase superfamily

Lin28: An inhibitor of microRNA biogenesis with roles in cancer and development	Noncatalytic effect of the ubiquitin ligase Hul5 on proteasome function

Protein kinase D signaling through substrate phosphorylation	Identification and characterization of novel inhibitors of Plasmodium falciparum hemozoin formation

Cellular and transcriptional analysis of endoderm patterning and organogenesis	The replicative fitness costs of drug resistance in HIV subtype C

The histone regulatory proteins Spt10 and Spt21: Roles in growth and silencing in Saccharomyces cerevisiae	The role of caudal genes in adult hematopoiesis and leukemogenesis

Biomechanical control of hematopoiesis	Sirtuin-mediated mechanisms of homeostasis and aging in metazoans

Role of the human TREX complex in mRNA export	ADAM9 metalloproteases and breast cancer cell migration

Characterization of the role of YidC in Escherichia coli membrane protein biogenesis	The role of the unfolded protein response in adipocyte formation and function

Identification of lipopolysaccharide transport and assembly proteins and characterization of an ABC transporter in this pathway as a potential antibiotic target	Regulatory mechanisms controlling temperature-dependent transcription of flagellar motility genes in Listeria monocytogenes

Molecular evolution in the Australo-Papuan fairy wrens (Aves: Maluridae)	Evolution and the emergence of structure

Alternative splicing networks in cell differentiation and programmed cell death	The roles of TIM-4 in innate and adaptive immunity

An unbiased, family-wide investigation of PDZ domain specificity	Technologies for sequencing and interpreting personal genomes

Transcription regulation of virulence gene expression in Francisella tularensis	RAS related cancer modeling and chemical genetics in the zebrafish

Vitamin K epoxide reductase homologues provide an alternative pathway for bacterial disulfide bond formation	Analyses of collagen XXII expression and function in non-small cell lung cancer

The Role of IKKepsilon in JAK/STAT Signaling During the Antiviral Immune Response	The Control of DNA Replication During Sporulation in Bacillus subtilis

Epigenetic Regulation of Multigene Families Mediates Virulence in Plasmodium falciparum Malaria	Regulatory pathways governing the transition to stationary phase in Bacillus subtilis

Regulation of RNA-mediated Heterochromatin Assembly in S. pombe	'Don't worry, I've got it covered!' -- Replication-independent nucleosome assembly and the maintenance of chromatin

The identification and elimination of immunosuppressive Mycobacterium bovis BCG genes to create novel rBCG vectors that generate increased CD8+ T cell responses	ESCRT-II links RNA localization to endosomal trafficking

Targeting the Anti-Apoptotic Protein MCL-1 in Human Cancer	Structural and Biochemical Studies of Lesion Recognition in Bacterial DNA Repair

Mechanisms of X-Chromosome Counting and Pairing in Mouse Embryonic Stem Cells	Biological design principles for synthetic biology

Protein Kinase D Signaling Through Substrate Phosphorylation in Endocytic Trafficking	The genetics and biochemistry of moenomycin biosynthesis

Role of VEGF in the adult: A tale of two epithelia	Massively parallel, targeted DNA resequencing and cardiovascular disease

Epigenetically driven tumor suppression by SNF5	The Molecular Evolution of Athletic Endurance in Humans

Bioorthogonal strategies to image nucleic acids, phospholipids, and sterols in cells	hnRNPs A1 and A2 Control Alternative Splicing of PK-M and Mediate Metabolic Programming of Cancer Cell Metabolism

Post-transcriptional regulation of let-7 microRNA expression in embryonic stem cells and cancer	The selective cost of misfolded proteins and a concomitant evolutionary adaptation

Single Molecule and Engineering Approaches to Studying RNA Synthesis and Energy Metabolism	Genome-wide location analysis of H-NS family members and studies of the control of cupA gene expression in P. aeruginosa

Small-molecule inducers of insulin expression in pancreatic alpha cells	Melanoma Cell Adhesion Molecule is Associated with Myogenicity in Multiple Progenitor Populations within Human Fetal Skeletal Muscle

Signaling and Feedback Networks Underlying Sensitivity and Resistance to Kinase Inhibitors in Oncogene Addicted Cancers	SREBP: A Key Effector of mTORC1 Signaling in Metabolism and Cancer

Phenomenological Models in Biological Physics: Cell polarity and rDNA transcription	Novel regulation of microRNA biogenesis and function

Bistability in Pseudomonas aeruginosa	Methods for Global Characterization of Chromatin Regulators in Human Cells

Mitochondrial Priming Determines Chemotherapeutic Response in Acute Myeloid Leukemia	Improving Zinc Finger Nucleases -- Strategies for Increasing Gene Editing Activities and Evaluating Off-Target Effects

Genome-wide integrative analysis of transcription factor occupancy and gene regulation in models of human cancer and cellular differentiation	Dissecting Protein-protein Interactions that Regulate the Spindle Checkpoint in Budding Yeast

Characterization Of The Mamu-A*01-Restricted Cd8-Positive T Lymphocyte Immunodominance Hierarchy In Simian Immunodeficiency Virus-Infected Rhesus Monkeys	Circadian Integration of Hepatic de novo Lipogenesis and Peripheral Energy Substrates Utilization

Mechanistic Studies of Vertebrate Hedgehog Signaling	Identification and characterization of novel drug resistance loci in Plasmodium falciparum