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You are viewing titles for HARVARD UNIVERSITY in the Biochemistry available through the UMI Dissertations & Thesis Gradwoorks site
 
The specificity of protein-DNA interactions
Synthesis and screening of spiroepoxy polycyclic small molecules
 
The M2 splice isoform of pyruvate kinase is a phosphotyrosine binding protein critical for tumor cell metabolism and proliferation
Histone dimers on the move: Nucleosome assembly systems for H2A and H2AV in Drosophila
 
DNA-templated synthesis and DNA-encoded reaction discovery in organic solvents
Metabolism and fate of marine archaea: Insights from compound-specific radiocarbon analysis
 
Synthesis and discovery of HDAC inhibitors using fluorous tags
Probing ramoplanin's inhibition in bacterial cell wall biosynthesis
 
Structure determination and interactions studies of the human gamma-glutamylcysteine synthetase light subunit by nuclear magnetic resonance
Structural and biochemical studies of bacterial nucleotide excision repair
 
Small molecule inhibitors of Plasmodium falciparum
Examination of the final steps in the biosynthesis of syringomycin E
 
YY1 functions in homologous recombination DNA repair and mice spermatogenesis
Targeting the bacterial cell wall-structural insight into peptidoglycan glycosyltransferases and moenomycin inhibition
 
Carrier protein tailoring, recognition, and applications for protein labeling
Biochemical and structural analysis of the protein machinery required for outer membrane protein biogenesis in Escherichia coli
 
Actin turnover dynamics in cells
Structural and mechanistic studies of the pantocin A biosynthesis
 
Probing transcriptional regulation in mammalian cells
Protein microarrays as diagnostic and prognostic tools
 
System-level studies of receptor tyrosine kinase signaling networks
Discovery and mechanistic characterization of a novel class of sonic hedgehog inhibitors
 
Wall teichoic acid biosynthesis as a novel antimicrobial target in Staphylococcus aureus
The SLX4/BTBD12 complex: A molecular toolkit for DNA repair
 
Chromatin-modifying enzymes of the 2-oxoglutarate and iron(II)-dependent oxygenase superfamily
Adaptor proteins regulate cellular functions in the context of a dynamic membrane interface
 
An in vitro translation, selection, and amplification system for peptide nucleic acids
Single-molecule studies of RNA aptamer binding
 
Identification of lipopolysaccharide transport and assembly proteins and characterization of an ABC transporter in this pathway as a potential antibiotic target
Microfluidic tools for studying the nematode Caenorhabditis elegans
 
Proteomic approaches to deciphering mechanisms of phosphotyrosine mediated signal transduction
Peptide inhibitors of bacterial cytokinesis
 
The structural basis for lesion search by the bacterial 8-oxoguanine DNA glycosylase MutM
Hepatitis B and C viruses alter cholesterol metabolism by novel mechanisms
 
Enhanced functional potential of nucleic acid aptamer libraries patterned to increase secondary structure
Single-molecule studies of Escherichia coli DNA replication
 
Biochemical and Genetic Studies of the Cyanobacterial Circadian Clock
Single-molecule fluorescence studies of telomerase assembly and catalysis
 
Single-Molecule Studies of Novel Protein-DNA Interactions
Of structure and function: The nature of the sonic hedgehog-heparan sulfate proteoglycan interaction
 
The Role of IKKepsilon in JAK/STAT Signaling During the Antiviral Immune Response
Regulatory pathways governing the transition to stationary phase in Bacillus subtilis
 
The Role of Outer Capsid Glycoprotein VP7 in Assembly, Neutralization, and Maturation of the Rotavirus Triple Layered Particle
Secretory Protein Biogenesis: From Membrane Translocation to Vitamin K-Dependent Disulfide Bridge Formation
 
Genome-wide ubiquitin & Ubl modification profiling in mitosis
Biosynthesis of N-P Bond Containing Peptide Natural Products
 
Inhibition by Small Molecules and Peptides of Dengue-virus Fusion and Entry
Structural and Biochemical Studies of Lesion Recognition in Bacterial DNA Repair
 
Mosaic nucleic acids that bind purine nucleotides
Structural and Biochemical Studies of UvrA, the Bacterial NER DNA Damage Sensor, and the Biochemical Characterization of a Bacterial MCM Protein
 
Biological design principles for synthetic biology
The genetics and biochemistry of moenomycin biosynthesis
 
Stapled Peptide Inhibition of Myc and the Androgen Receptor
AGC kinases: New targets and crosstalk nodes
 
Novel Routing of Prephenate to Natural Products
Bioorthogonal strategies to image nucleic acids, phospholipids, and sterols in cells
 
Point-of-Care Diagnostics and Mechanisms of Protein Denaturation
Studying cytokinesis using small molecule tools
 
An Oligonucleotide Seqence Targeting the CR4-CR5 Region of the Human Telomerase RNA
Rewiring thiol-redox pathways of electron transfer in Escherichia coli
 
Characterization of Enzymes Involved in Peptidoglycan Biogenesis
Small-molecule inducers of insulin expression in pancreatic alpha cells
 
Small-molecule suppressors of cytokine-induced beta-cell apoptosis
Structural Analysis of the CDK-Cyclin Complex of Pho85-Pho80 and Genome-Wide Characterization of the Phosphate Starvation Response in Schizosaccharomyces pombe
 
Elucidating the regulation and effectors of the breast cancer oncogene, IKKepsilon
Using Live Cell Imaging to Probe Biogenesis of the Gram-negative Cell Envelope
 
The Facilitation of Protein-DNA Search and Recognition by Multiple Modes of Binding
Architecture and regulation of the arenavirus polymerase complex
 
Physical models for the early evolution of cell membranes
Gene-drug interactions and the evolution of antibiotic resistance
 
A Biochemical Investigation of the Mechanism of Transport of DNA by SpoIIIE During Sporulation in Bacillus subtilis: Probing the Transmembrane Domain, the alpha Domain, and the Hinge Region