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COLUMBIA UNIVERSITY
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You are viewing titles for COLUMBIA UNIVERSITY in the Molecular biology available through the UMI Dissertations & Thesis Gradwoorks site
Reconstructing the evolutionary and population history of an introduced carnivore, the small Indian mongoose (Herpestes javanicus) (Carnivora: Herpestidae): Inferences from mitochondrial and nuclear sequence data
Statistical characterization and prediction of transmembrane protein structures with Bayesian networks
Dynamic role of ubiquitination in the p53 pathway
Functional studies of mRNA 3'-end formation and transcription termination
Altered phosphoinositide metabolism in familial Alzheimer's disease
BAF180 mutations and the estrogen receptor pathway in breast cancer
Visualizing metabolic control: Crystal structures of fission yeast AMPK homologs with regulatory ligands
Altered synaptic assembly and neuronal morphology in a mouse model of schizophrenia susceptibility associated with the 22q11.2 locus
The role of Blimp-1 in T-lymphocyte homeostasis and function
Complex interactions between Rqh1, Eme1 and Swi5 maintain genomic stability in Schizosaccharomyces pombe
Role of the BARD1 tumor suppressor in genomic stability
The transcriptional repressor Blimp-1 in epidermal terminal differentiation
Determination of cleavage and polyadenylation factor 73 (CPSF-73) as the endoribonuclease involved in pre-mRNA 3' processing
Thinking outside the vulva: A non-vulval perspective on vulval development
Analysis and prediction of natively unstructured regions in proteins: Refining the structure-function paradigm
Inter-Kingdom Horizontal Gene Transfer: A new mechanism for the acquisition of Legionella pneumophila Type IV effectors
Mechanistic studies of the ARF-p53 tumor suppressor pathway
Remodeling of the ryanodine receptor complex during muscle stress
Dynamics of the Rad51 nucleoprotein filament
Structural and functional studies of carnitine acyltransferases
New insights into the regulation of Chk2 stability and turnover
Four-color DNA sequencing by synthesis on a chip using cleavable fluorescent nucleotide reversible terminators
Development and evolution of a laryngeal specific Myosin Heavy Chain in African Clawed frogs
Novel molecular adaptations for stress response in Candida albicans through Cas5 and Snf1
Neurogenesis and synaptogenesis in the enteric nervous system: Molecules that generate neuronal phenotypic and synaptic diversity
Analysis of PTEN function and regulation
Three RINGS and control of apoptotic JNK signaling and neuronal cell death
Novel regulatory roles of SUMO modification in mammalian pre-mRNA 3' end processing
Development of new DNA sequencing approaches and investigation of vision-related proteins using synthetic chemistry
Role of hairless in epidermal proliferation
Functional role of the adapter protein EFS/Sin in thymic medullary development and autoimmunity
Identification of target genes of the transcription factor Zfx in embryonic stem cells
The contribution of impaired Nogo receptor function and miRNA biogenesis alterations to 22q11DS-associated psychiatric and cognitive deficits
Imaging-guided microarray identifies molecular markers in schizophrenia and Parkinson's disease
c-Abl signaling in lymphocytes and fibroblasts: Cell type-dependent effects on activation and apoptosis
Molecular mechanisms of cell fate specification in Drosophila limb development
The role of Rad55, Rad57, and MAT heterozygosity in homologous recombination
Uncovering the mechanism and genetic control of break-induced replication
The role of the alternative splicing factor MEC-8: Its uses in creating conditional gene expression and RNAi in C. elegans
Genes that act in specification of the vulval secondary fate in Caenorhabditis elegans
DBC1 and MSL2, two novel members of the p53 signaling network
Retinal projections of the optic chiasm: To cross or not to cross
A specialized vascular niche for adult neural stem cells
The role of Fanconi anemia proteins in DNA replication and repair
The ESCRT machinery, required for endosomal trafficking, is a pH-signaling platform
Investigating the role of Rad51 in Homologous Recombination at the single molecule level
Structural and biochemical characterization of the S. cerevisiae AMPK homolog SNF1
Characterization of neuronal plakins
Post-translational modification of the ribonucleotide reductase inhibitor, Sml1, in response to DNA damage
3'UTR-dependent mechanisms of gene regulation
The role of calcium-permeable kainate receptors in neurite outgrowth and synapse formation between nociceptive dorsal root ganglion and spinal cord dorsal horn neurons
Developmental regulation of ponto-cerebellar mossy fiber connectivity
Structural plasticity and conformational transitions of biological macromolecules: HIV gp120
Discovery of Mdm2 E3 ligase inhibitors using a cell-based auto-ubiquitination assay
Studies on the response to DNA double-strand breaks: Damage-dependent phosphorylations and DNA end resection
Molecular mechanisms underlying the functional integration of adult-born hippocampal neurons - implications for depression and anxiety
A novel assay for break-induced replication reveals a role for resection
DNA methylation in health and disease: Breast cancer and depression
The role of Cbp3p in cytochrome b expression and assembly into coenzyme QH2 -- cytochrome c reductase
Anthrax toxin receptors: Evaluation of receptor function in angiogenesis and development
Understanding the role of NF-kappaB RelA subunit in TLR and RLR pathways
The role of translocated in liposarcoma in transcription
Connective tissue growth factor (CCN2/CTGF)-induced fibrogenesis: Biology, bioengineering and therapeutics
Analysis of mitochondrial SCO proteins in mammals: Relevance to human mitochondrial disease
Ubiquitination regulates distinct cellular pathways in tumorigenesis
Revisiting the adaptor hypothesis: Studies of ribosomal selection of misacylated tRNAs
Mechanistic studies of interferon alpha accelerated lupus
Molecular bases for the functional consequences of the mouse mutation Mahoganoid (Mgrn1md)
Mechanism study of radiation induced bystander effect in vivo using the gpt delta transgenic mouse model
Specification of Functional Motor Neuron Diversity from Embryonic Stem Cells
The role of Notch in Neuroblastoma Angiogenesis
The Stereoselectivity of the Escherichia coli Protein Synthesis Machinery
A Genetic and Biochemical Study of Yor1p Activity and Biogenesis
A Genetic and Biochemical Study of Sec24p Functions in COPII Biogenesis
Histone Acetylation and the Aging Hippocampus
The role of BLIMP1 and A20 inactivation in the pathogenesis of diffuse large B-cell lymphoma
New Insights Into the RING Domains of Mdm2 and MdmX
Role of phospholipid interactions and protein oligomerization in the conformational reaction cycle of SecA
Investigating the Role of the Amyloid Precursor Protein in the Pathogenesis of Alzheimer's Disease
Effects of DNA Shape and Sequence of Protein-DNA Recognition
The Hydrolysis of PI(4,5)P2 by the Synaptojanin-Endophilin Partnership Is Modulated by Membrane Curvature and Facilitates Membrane Fission
Genome Wide Analysis of Neural Differentiation and Left/Right Asymmetry in Caenorhabditis elegans
Notch Regulates Macrophage Function During Inflammation and Angiogenesis
DNA End Resection in Saccharomyces cerevisiae: Mechanism and Implications
Transcriptional Regulation of DAF-16 Target Genes in C. elegans
Notch Affects Endothelial Cell Behavior through Regulation of Integrin Expression
The search for Holliday junction resolvases that promote mitotic crossovers in Saccharomyces cerevisiae
Characterizing the Interaction of the ATP Binding Cassette Transporters (G subfamily) with the Intracellular Protein Lipid Environment
Negative regulation of gene expression by the tumor suppressor p53
The role of Brdt, a double bromodomain testis-specific protein, in spermatogenesis: Chromatin organization and mRNA splicing
Trans-acting factors affecting retroviral recoding
Using machine learning to predict gene expression and discover sequence motifs
Complex Regulation of Pax6 Neuronal Progenitors By Rb Family Members During Corticogenesis
Obesity and Aggressive Prostate Cancer Bias and Biomarkers
The Role of Hiwi in Stem Cell Maintenance and Sarcomagenesis
Causation and Explanation in Molecular Developmental Biology
Determining the Role of Trib3 in Neuronal Apoptosis
A functional role for transfer RNA-derived microRNAs in human B cells
Non-autonomous regulation of bone mass accrual and the role of T-cell protein tyrosine phosphatase in the bone regulation of insulin sensitivity
Notch deficiency leads to arteriovenous malformations and altered pericyte function