Nursing turnover is a costly problem in today’s healthcare environment, and particularly problematic is the rapid turnover within the first year of employment. When an organization experiences rapid turnover within the first few months, orientation of new nurses can incur increased costs. One reason widely cited for rapid nursing turnover is the lack of preparation during nursing orientation. This study sought to gain an understanding about the experiences of nurses in a major managed care organization who participated in new hire orientation utilizing blended learning strategies that combine traditional classroom orientation activities, web-based educational interactive sessions, online sessions, and preceptors. Additionally, the study sought to gain an understanding of the effect adult learning styles had on the orientation experiences. This study utilized a case study design to explore the learning style of nurses, and their experiences during new hire orientation, utilizing a blended learning approach. The nurse participants each completed a Learning Style Survey, in order to assess each participant’s dominant learning style. Participants either participated in an interview or in an online survey questionnaire. The findings indicated the nurse participants in this study possess various learning styles and preferential learning strategies or modalities. With the various teaching strategies utilized in this study, the findings indicated that there are several effective learning approaches or modalities, and each may be effective, depending on the learning style of the student, and the material being presented. The findings from this study could provide educators with a greater understanding of the adult learners learning styles and needs, in order to design programs to better meet the adult learners needs, and improve learning outcomes.