The population of African immigrants in the USA almost doubled in the period between the year 2000 and the year 2006. One of the most important economic opportunities attracting immigrants to the USA is the possibility of starting a business. The research field of immigrant entrepreneurship is part of the discipline of international entrepreneurship because immigrant entrepreneurship involves the exploitation of opportunities across national borders. The research problem that was addressed in this quantitative, non-experimental, correlational study was that the existing theories used in explaining immigrant entrepreneurial activity do not include human capital to justify the divergent entrepreneurial trajectories of African immigrants in the USA. Researchers have identified the need to expand the examination of individual ethnic and immigrant groups in order to understand better the phenomenon of entrepreneurial activity as it relates to the human capital of individual groups, such as African immigrants. Data were collected through a web-based survey. Items on the survey were aligned to the research problem by including questions focusing on participants' human capital, such as level of education, work experience, and business ownership experience. In addition, the survey contained questions regarding participants' involvement in entrepreneurial activities, such as consciously planning to set up a business, identifying opportunities, and pursuing opportunities. Spearman's correlation coefficients were calculated to test the relationship between the participants' human capital and their entrepreneurial activity. Participants were selected by purposive sampling of African immigrants aged 18 years and over, living in any of the 50 states comprising the USA. Results indicated no statistically significant relationship between the human capital elements of education,r_s(62) = .03, p = .81, work experience, r _s(58) = .05, p = .69, and entrepreneurial activity. Results showed a positive and statistically significant relationship between business ownership experience and entrepreneurial activity, r_s(61) = .67, p < .01. Policy makers should design programs that increase the numbers of African immigrants who gain business ownership experience. Future qualitative studies should provide more depth to the findings of this study by exploring the factors influencing entrepreneurial activity among African immigrants in the USA.