The experience of love is a phenomenon that human beings often spend their lives seeking. In fact, researchers have found that the experience of love or being in love is universal and prevalent across cultures. Not only has love been examined as a fundamental component of the human experience, it has been argued that love should be considered the most fundamental human need. When love is reciprocated, individuals report feeling elated and happy; however, when love is one-sided, individuals report feeling both emotional and physiological pain. Researchers have found that unrequited love is prevalent in our society as almost everyone can recall an experience with non-reciprocated affection. This dark side of love relationships has been studied extensively to aid researchers in understanding why some relationships thrive while others fail to form. Scholars have written extensively on the antecedents of unrequited love, however, less scholarship has been devoted to examining the physiological, emotional, and relational outcomes of unrequited love relationships. The current study examined the physiological, emotional, and relational outcomes that heretofore have not been fully considered, such as how the human stress response affects and is affected by unrequited love relationships. Results of this study indicate that the experience of unrequited love may not elicit the negative emotions researchers previously identified as related to the experience of one sided attraction. Future research on unrequited love should examine positive affect as well as targets' and pursuers' experiences with negative affect.