Animal-Assisted therapy is an area of psychology in great need of further research. While the relationship between domesticated animals and humans dates back throughout human history, the relationship between animal co-therapists, an animal that is partnered with a licensed mental health worker for goal directed therapy, and clients seeking mental health services, is a relatively new phenomenon. As a result, the empirical evidence is limited. The studies that have been conducted generally look at the effect of animals on an individual's anxiety, loneliness, and physical health; however, there has not been a study conducted which attempts to look at and understand this unique relationship between humans and animals. This study focuses on this very special, and little understood, relationship. In-depth interviews with therapists who utilize animal co-therapists were conducted, transcribed, and analyzed, with the goal of providing insight into this relationship in order to help guide future research and enhance the appreciation of the power in the human-animal bond. Findings indicate that the relationships that exist and develop between the therapist, animal, and client contains elements apparent in an established therapeutic relationship: Trust and a Sense of Safety, Acceptance, Empathy, and Respect.