Anticipating and exceeding patient needs are some of the greatest challenges of healthcare executives. The problem providing the impetus to the current study is patient dissatisfaction with the information provided to them. The purpose of the current comparative study was to analyze the extent to which satisfaction with nursing communication differs based on the patient's gender, age, and ethnicity. A secondary purpose was to determine whether patients were more or less satisfied with particular aspects of nursing communication. The convenience sample included 105 respondents from patient populations on three progressive care units at a public teaching hospital in Texas. The Nursing Outcome Classification tool was used to measure the outcome of patient satisfaction with nurse communication. The demographic variables were measured using nominal, ordinal, and categorical scales. Therefore, crosstab analyses using Pearson's chi-square tests were used to examine relationships among the demographic variables. One-way ANOVAs and MANOVAs were conducted to examine the potential effects of age group, gender, and ethnicity on patient satisfaction with communication. In order to examine potential differences between item responses, repeated measures analysis was conducted using items as the within subjects effect. Based on current study results, patient ratings of satisfaction with nurse communication did not differ based on the patient's age group, gender, or ethnicity. There were differences in item responses; patients were significantly more satisfied with nurse introduction compared to the exchange of information. Although patient satisfaction ratings did not differ in the study, the methodology could be used to advance the discussion of measuring patient satisfaction with nurse communication.