The purpose of this study was to design and evaluate a camp intervention targeting independence among children, adolescents, and young adults with spina bifida. An intervention sensitive to the cognitive challenges of this population was embedded within a typical camp experience. Over the course of five days, campers attended daily group sessions about memory, problem-solving, and social skills as well as individual meetings with camp counselors to discuss goals. Camper and parent report of demographic variables, goal attainment, knowledge of spina bifida, independence, and psychosocial functioning were gathered before, during, and after camp. Interventionist report of camper participation in the intervention, camp counselor quality, and adherence to the treatment manual were also collected. Within subjects Analysis of Variance indicated that campers made statistically significant gains in individual goals, management of spina bifida responsibilities, and independence with general spina bifida tasks, with medium effect sizes observed in goal attainment. Moderator analyses suggested that outcomes did not vary by demographic or camp factors. Mediational analyses examining the relationship between dose of the intervention and outcomes were not supported. Results indicate that individual goals were most impacted following participation in camp. Strategies to improve methodology for evaluating camp interventions are discussed.