Neural substrates and mechanisms underlying semantic fluency deficit in traumatic brain injured adults
by Ngo, Catherine Trinh, Ph.D., THE GEORGE WASHINGTON UNIVERSITY, 2007, 109 pages; 3275149

Abstract:

This investigation sought to understand the cognitive and neural bases for semantic fluency deficit in traumatic brain injured older adults. Studies 1 and 2 demonstrated that right frontal-temporal lesion patients performed poorly on a verbal semantic task (repeated trials category fluency) and a non-verbal semantic task (vocabulary and object-function matching), but performed comparably with controls on a phonemic fluency task (letter fluency). These results suggest that the semantic fluency deficit is not due to a difficulty with word retrieval, but is rather due to a fundamental breakdown in semantic knowledge stores. Consistent with this interpretation, the results of Study 3 using the Analysis of Brain Lesions program (Makale et al., 2002; Solomon et al., 2007) suggest the brain basis of the observed deficit in the anterior temporal region.

 
AdviserStephen Dopkins
SchoolTHE GEORGE WASHINGTON UNIVERSITY
SourceDAI/B 68-08, p. , Nov 2007
Source TypeDissertation
SubjectsNeurosciences; Cognitive psychology
Publication Number3275149
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