The problem that this study sought to examine was the relationship of employee wellness (i.e., factors of stress, exercise, and obesity) relative to job performance among hospital employees located in a mid-western US city. The sample included 89 females and 14 males with the largest percentage of respondents in the 36-45 age group. This study utilized a descriptive quantitative approach based on a correlation design to explore the above factors. Results showed that there was a significant inverse relationship between stress and job performance. That is, those employees experiencing more stress had lower job performance scores while those employees who managed their stress more effectively had better scores overall. In addition, there was a positive relationship between exercise and job performance. In other words, those employees who exercised regularly had better job performance scores than their more sedentary counterparts. Finally, there was an inverse relationship between being overweight and job performance. Specifically, those employees who were within their ideal weight range were more likely to have a higher job performance score than their overweight counterparts. The hypotheses tested in this research supported the concept of wellness programming for employees. Finally, this study provides a format for other research in similar structured organizations who seek to improve their employees performance while on the job via a wellness program. Use of such comparisons among other organizations of a similar design could help such organizations guide their wellness programs in a manner that would make them more beneficial for their employees as well as businesses.