The nursing shortage and nurse turnover continues to challenge the hospice industry. Job satisfaction and intention to leave among hospice nurses in a for-profit corporation was studied to determine why hospice nurses leave the corporation. Using a quasi-experimental correlational survey design, this study administered the Minnesota Satisfaction Questionnaire (MSQ) short-form and the Anticipated Turnover Scale (ATS) to 777 hospice nurses in 60 sites located in 14 states of a nationwide corporation. A total of 302 surveys were returned equating to a 39% response rate. The results of the Pearson's r correlations determined that the hospice nurse's intention to leave score had significant negative correlations with all three types of satisfaction including general satisfaction, intrinsic satisfaction, and extrinsic satisfaction. Using correlations, MANOVA, and as a step-down analysis two multiple regression models, it was also revealed that there were no significant differences on the relationship between job satisfaction and intention to leave by any of the hospice nurse demographic variables of age, level of education, ethnicity, tenure in nursing, and/or job tenure.