Stress-related work problems within the American workforce contribute over 30 billion dollars in lost revenues annually. Researchers have documented that, in healthcare, stress and work are deadly combinations. Healthcare professionals, physicians, nurses, and other allied health professionals, are impacted by the demands within the healthcare environment as well as within their personal lives. Studies on nonprofessional healthcare providers, however, are less prevalent. The goal of the present study is to discover predictors for stress-related loss of work for nursing assistants delivering direct patient care. Data from the National Nursing Assistant Survey of 20042005 were analyzed to ascertain the relationship of job satisfaction to various work and personal stress-inducing variables upon nursing assistants. Results supported the hypothesis that a significant relationship exists between job-related stress, indicated by complaints about the job, and loss of work due to childcare, on-the-job discrimination, and poor pay. Limitations and suggestions for further research were discussed.