Design, Simulation, and Experimental Studies of Neural Prosthetic Interface Device
by Chu, Stephen, M.S., UNIVERSITY OF CALIFORNIA, IRVINE, 2011, 36 pages; 1493986

Abstract:

The field of prosthetics has come a long way, but still leaves much to be desired. In this paper, the feasibility of implementing an interface between a neural probe and the brachial plexus is explored through computer modeling and experimental data. Computer simulations track the organic compounds sucrose, dextran, and carmine within a nerve trunk to infer the behavior of VGF, a nerve growth factor. Experiments are also performed to track carmine diffusing through the giant axon of a squid, and correlated with simulation data. A model of the experiment was used to approximate the diffusion coefficient of carmine, and then compared to the simulation data of sucrose for consistency. A model of the channel in the probe was also made to characterize the flow of fluid within the probe.

The comparison of simulation and experimental data prove the simulations to be believable. A hypothetical simulation involving VGF show that using diffusion as a method of distribution is plausible. The channel found within the probe has also found to have acceptable behavior through simulation work.

 
AdviserWilliam C. Tang
SchoolUNIVERSITY OF CALIFORNIA, IRVINE
SourceMAI/ 49-06, p. , Jul 2011
Source TypeThesis
SubjectsBiomedical engineering; Electrical engineering
Publication Number1493986
Adobe PDF Access the complete dissertation:
 

» Find an electronic copy at your library.
  Use the link below to access a full citation record of this graduate work:
  http://gateway.proquest.com/openurl%3furl_ver=Z39.88-2004%26res_dat=xri:pqdiss%26rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation%26rft_dat=xri:pqdiss:1493986
  If your library subscribes to the ProQuest Dissertations & Theses (PQDT) database, you may be entitled to a free electronic version of this graduate work. If not, you will have the option to purchase one, and access a 24 page preview for free (if available).

About ProQuest Dissertations & Theses
With over 2.3 million records, the ProQuest Dissertations & Theses (PQDT) database is the most comprehensive collection of dissertations and theses in the world. It is the database of record for graduate research.

The database includes citations of graduate works ranging from the first U.S. dissertation, accepted in 1861, to those accepted as recently as last semester. Of the 2.3 million graduate works included in the database, ProQuest offers more than 1.9 million in full text formats. Of those, over 860,000 are available in PDF format. More than 60,000 dissertations and theses are added to the database each year.

If you have questions, please feel free to visit the ProQuest Web site - http://www.proquest.com - or call ProQuest Hotline Customer Support at 1-800-521-3042.