Older clinical reports have shown that the prevalence of bipolar disorder is rare among African Americans. However recent research has shown that in the United States, major psychoses are probably equally prevalent across racial groups. It has been reported that racial differences are eliminated in the clinical diagnosis of psychotic disorders when structured diagnostic interviews and criteria are strictly adhered to. Previous research has shown that African Americans with bipolar are more likely to have psychotic symptoms and present with more irritable symptoms which can be misinterpreted as psychosis, thus causing them to be overdiagnosed with schizophrenia. Stimulated by these considerations, the examiner seeks to further investigate whether African-American outpatients were more likely to have their diagnosis changed from schizophrenia to a mood disorder rather than vice versa. Presumably diagnostic changes are as a result of additional information, a more thorough evaluation and therefore are more valid. A random sample was taken from 155 outpatients seen at Howard University Mental Health Clinic for outpatient psychiatric care. Results revealed that the number of outpatients with an initial diagnosis of schizophrenia were significantly more likely to change to a mood syndrome disorder than outpatients without schizophrenia were likely to have their diagnosis changed to schizophrenia.