Do patterns of physical activity mirror the disease activity in the patients with early rheumatoid arthritis?
by Patel, Nileshkumar R., M.S.P.T., MGH INSTITUTE OF HEALTH PROFESSIONS, 2008, 50 pages; 1452404

Abstract:

Purpose. (i) Describe patterns of disease activity, physical activity and function in patients with early RA (ii) Investigate relationships between these variables over one year. Methods. 210 patients with early RA participated in the “Brigham and Women's Hospital Rheumatoid Arthritis Sequential Study (BRASS) registry”. We measured demographics, disease activity (DAS28-CRP3), function (MDHAQ) and minutes of moderate physical activity at baseline and 1 year. Results . Disease activity decreased (p<0.001) and function improved (p<0.001) over one year. Correlations between DAS28-CRP3 and MDHAQ were moderate at baseline (rho=0.46, p<0.001) and 1 year (rho=0.46, p<0.001). The correlation between physical activity and disease activity was weak but significant at baseline (rho=0.21, p<0.01) and 1 year (rho=0.21, p=0.02) with no change in total minutes noted. Conclusion. Despite significant reductions in disease activity and improvements in function, physical activity remained constant in the subjects indicating the need for appropriate counseling regarding physical activity in early RA.

 
AdviserMaura Daly Iversen
SchoolMGH INSTITUTE OF HEALTH PROFESSIONS
SourceMAI/ 46-05, p. , May 2008
Source TypeThesis
SubjectsPhysical therapy
Publication Number1452404
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