The relationship between level of education, minority status, age of diagnosis, and caregiver stress among 186 parents of autistic children was investigated. They were recruited to an online survey through 10 online Autism support groups. Caregiver stress was determined by a modified, self report, Zarit Burden Interview. The results indicated that parents with higher levels of education reported greater feelings of burden than parents with lower levels of education. Caucasians did not significantly differ from other minority groups (excluding Asians). Finally, a younger age of diagnosis was associated with higher levels of stress. In sum, these findings provided partial support for the Transactional Model of Stress and Coping, which states that stress is a transaction between an individual and the environment in which the overall impact of the stressor is mediated by the individual's ability to adapt. These findings also support the position that early screening and diagnosis for autism is vital for the well-being of the parents.